Rachel Chalmers , Guy Robinson , Harriet Risby , Kristin Elwin , Rebecca Howarth , Felicity Simkin , Andrew Nelson
{"title":"隐孢子虫参考微生物学服务的转型,以应对同一个健康挑战","authors":"Rachel Chalmers , Guy Robinson , Harriet Risby , Kristin Elwin , Rebecca Howarth , Felicity Simkin , Andrew Nelson","doi":"10.1016/j.fawpar.2025.e00274","DOIUrl":null,"url":null,"abstract":"<div><div><em>Cryptosporidium</em> has a wide range of hosts and routes of transmission, so public health investigations require <em>Cryptosporidium</em> species identification and discriminatory typing to enhance the microbiological evidence provided by routine diagnostic tests. A pioneering seven-locus genotyping scheme, based on multilocus variable number of tandem repeats analysis, has been validated and implemented for <em>Cryptosporidium parvum</em> by the national Cryptosporidium Reference Unit for England and Wales. In this paper, the journey to implementation as a service to support disease surveillance, epidemiology and outbreak investigations, and the resultant benefits to public health activities are described.</div></div>","PeriodicalId":37941,"journal":{"name":"Food and Waterborne Parasitology","volume":"40 ","pages":"Article e00274"},"PeriodicalIF":2.9000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The transformation of a Cryptosporidium reference microbiology service to tackle the One Health challenge\",\"authors\":\"Rachel Chalmers , Guy Robinson , Harriet Risby , Kristin Elwin , Rebecca Howarth , Felicity Simkin , Andrew Nelson\",\"doi\":\"10.1016/j.fawpar.2025.e00274\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div><em>Cryptosporidium</em> has a wide range of hosts and routes of transmission, so public health investigations require <em>Cryptosporidium</em> species identification and discriminatory typing to enhance the microbiological evidence provided by routine diagnostic tests. A pioneering seven-locus genotyping scheme, based on multilocus variable number of tandem repeats analysis, has been validated and implemented for <em>Cryptosporidium parvum</em> by the national Cryptosporidium Reference Unit for England and Wales. In this paper, the journey to implementation as a service to support disease surveillance, epidemiology and outbreak investigations, and the resultant benefits to public health activities are described.</div></div>\",\"PeriodicalId\":37941,\"journal\":{\"name\":\"Food and Waterborne Parasitology\",\"volume\":\"40 \",\"pages\":\"Article e00274\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Food and Waterborne Parasitology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2405676625000216\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PARASITOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food and Waterborne Parasitology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405676625000216","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PARASITOLOGY","Score":null,"Total":0}
The transformation of a Cryptosporidium reference microbiology service to tackle the One Health challenge
Cryptosporidium has a wide range of hosts and routes of transmission, so public health investigations require Cryptosporidium species identification and discriminatory typing to enhance the microbiological evidence provided by routine diagnostic tests. A pioneering seven-locus genotyping scheme, based on multilocus variable number of tandem repeats analysis, has been validated and implemented for Cryptosporidium parvum by the national Cryptosporidium Reference Unit for England and Wales. In this paper, the journey to implementation as a service to support disease surveillance, epidemiology and outbreak investigations, and the resultant benefits to public health activities are described.
期刊介绍:
Food and Waterborne Parasitology publishes high quality papers containing original research findings, investigative reports, and scientific proceedings on parasites which are transmitted to humans via the consumption of food or water. The relevant parasites include protozoa, nematodes, cestodes and trematodes which are transmitted by food or water and capable of infecting humans. Pertinent food includes products of animal or plant origin which are domestic or wild, and consumed by humans. Animals and plants from both terrestrial and aquatic sources are included, as well as studies related to potable and other types of water which serve to harbor, perpetuate or disseminate food and waterborne parasites. Studies dealing with prevalence, transmission, epidemiology, risk assessment and mitigation, including control measures and test methodologies for parasites in food and water are of particular interest. Evidence of the emergence of such parasites and interactions among domestic animals, wildlife and humans are of interest. The impact of parasites on the health and welfare of humans is viewed as very important and within scope of the journal. Manuscripts with scientifically generated information on associations between food and waterborne parasitic diseases and lifestyle, culture and economies are also welcome. Studies involving animal experiments must meet the International Guiding Principles for Biomedical Research Involving Animals as issued by the Council for International Organizations of Medical Sciences.