2021年至2023年间巴西心力衰竭严重程度和死亡率相关因素

IF 3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology Pub Date : 2025-06-30 DOI:10.1016/j.cpcardiol.2025.103122

Jean-Paul Paluku Mwalitsa MD , Jean-Paulin Mbo Mukongole PhD , Zacharie Tsongo Kibendelwa PhD , Dalton Kambale Munyambalu MD , Serge Muyisa Sahika MD , François Katsuva Mbahweka MD , Fiston Nzanzu Arma MD , Roland Muhindo Muyisa MD , Ngesera Kambale MD , Adélar Nzanzu Kalima MD , Claude Kasereka Masumbuko PhD

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引用次数: 0

摘要

背景：心力衰竭是一种高发病率和死亡率的综合征，受多种区域因素的影响。目的：本研究旨在通过识别可改善刚果民主共和国东部患者生活质量和生存率的因素来加强心力衰竭管理。方法：本描述性分析研究于2022年1月1日至2023年12月31日进行，纳入156例心力衰竭患者（平均年龄62±15岁），其中男性80例，女性76例。每位患者随访12个月。结果：心内科中心2732例患者中有156例心衰发生率为17.5%。严重程度与使用本土抗毒产品（p 0.000）和瓣膜性心脏病（p 0.000）相关。使用本土抗毒产品对死亡率有显著影响(41.2%死亡率；P 0.000)，糖尿病病程(≤1年7.4%；2-5年11.1%；> 5年33.3%；P 0.014)，扩张型心肌病(18.9% vs. 1.2%；P 0.000)和瓣膜性心脏病(17.5% vs. 1.3%；p 0.003)。死亡率因心力衰竭表型而异(HFrEF 30.9%, HFmEF 5.1%, HFpEF 0.0%；p 0.000)和严重程度（NYHA IV 55.6% vs. NYHA I和II 0.0%）。结论：国产抗毒制剂和风湿性心瓣膜病与心力衰竭患者病情恶化及过早死亡有关。解决这些因素可能会提高该地区患者的生存率。

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Factors associated with heart failure severity and mortality in Butembo between 2021 and 2023

Background

Heart failure is a syndrome with high morbidity and mortality, influenced by various regional factors.

Objective

This study aimed to enhance heart failure management by identifying factors that can improve the quality of life and survival of patients in eastern DR Congo.

Methods

Conducted from January 1, 2022, to December 31, 2023, this descriptive analytical study included 156 heart failure patients (mean age 62 ± 15), comprising 80 males and 76 females. Each patient was followed for 12 months.

Results

The frequency of heart failure was 17.5 % (156 out of 2732 patients) at the cardiology center. Severity correlated with the use of indigenous anti-poison products (p 0.000) and valvular heart disease (p 0.000). Mortality was notably influenced by indigenous anti-poison product use (41.2 % mortality; p 0.000), duration of diabetes (≤ 1 year 7.4 %; 2-5 years 11.1 %; > 5 years 33.3 %; p 0.014), dilated cardiomyopathy (18.9 % vs. 1.2 % for non-dilated; p 0.000), and valvular heart disease (17.5 % vs. 1.3 %; p 0.003). Mortality rates varied by heart failure phenotype (HFrEF 30.9 %, HFmEF 5.1 %, HFpEF 0.0 %; p 0.000) and severity (NYHA IV 55.6 % vs. NYHA I and II 0.0 %).

Conclusion

Indigenous anti-poison products and rheumatic valvular heart disease contribute to the worsening and premature death of heart failure patients. Addressing these factors may improve patient survival in this region.

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来源期刊

Current Problems in Cardiology 医学-心血管系统

CiteScore

4.80

自引率

2.40%

发文量

392

审稿时长

6 days

期刊介绍： Under the editorial leadership of noted cardiologist Dr. Hector O. Ventura, Current Problems in Cardiology provides focused, comprehensive coverage of important clinical topics in cardiology. Each monthly issues, addresses a selected clinical problem or condition, including pathophysiology, invasive and noninvasive diagnosis, drug therapy, surgical management, and rehabilitation; or explores the clinical applications of a diagnostic modality or a particular category of drugs. Critical commentary from the distinguished editorial board accompanies each monograph, providing readers with additional insights. An extensive bibliography in each issue saves hours of library research.