nir诱导的光电开关杂化DNA纳米结构药物递送系统用于干细胞命运的时空控制（Small 26/2025）

IF 12.1 2区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Small Pub Date : 2025-07-04 DOI:10.1002/smll.202570207

Thanapat Pongkulapa, Ji Hye Yum, Callan D. McLoughlin, Brandon Conklin, Tomotaka Kumagai, Li Ling Goldston, Hiroshi Sugiyama, Soyoung Park, Ki-Bum Lee

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引用次数: 0

摘要

在纳米医学中，药物有效载荷的有效控制和可预测的释放对治疗效果至关重要。与被动药物释放相反，光是控制生物功能的有吸引力的工具，提供无与伦比的时间和空间精度。利用这一潜力，光响应DNA纳米结构和能够利用近红外信号的上转换纳米颗粒的结合为精细调节动态和复杂的干细胞命运调控提供了一条有前途的途径。更多见文章编号2409530，朴素英，李基范和同事。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

NIR-Induced Photoswitching Hybrid DNA Nanoconstruct-Based Drug Delivery System for Spatiotemporal Control of Stem Cell Fate (Small 26/2025)

查看原文本刊更多论文

NIR-Induced Photoswitching Hybrid DNA Nanoconstruct-Based Drug Delivery System for Spatiotemporal Control of Stem Cell Fate (Small 26/2025)

Drug Delivery

Within nanomedicine, efficient control and predictable release of drug payloads are crucial to therapeutic efficacy. Opposing passive drug release, light is an attractive tool for controlling biological functions, offering unparalleled temporal and spatial precision. Leveraging this potential, the combination of photo-responsive DNA nanostructures and up-conversion nanoparticles capable of harnessing near-infrared signals presents a promising avenue for finely tuning dynamic and intricate stem cell fate regulation. More in article number 2409530, Soyoung Park, Ki-Bum Lee, and co-workers.

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来源期刊

Small 工程技术-材料科学：综合

CiteScore

17.70

自引率

3.80%

发文量

1830

审稿时长

2.1 months

期刊介绍： Small serves as an exceptional platform for both experimental and theoretical studies in fundamental and applied interdisciplinary research at the nano- and microscale. The journal offers a compelling mix of peer-reviewed Research Articles, Reviews, Perspectives, and Comments. With a remarkable 2022 Journal Impact Factor of 13.3 (Journal Citation Reports from Clarivate Analytics, 2023), Small remains among the top multidisciplinary journals, covering a wide range of topics at the interface of materials science, chemistry, physics, engineering, medicine, and biology. Small's readership includes biochemists, biologists, biomedical scientists, chemists, engineers, information technologists, materials scientists, physicists, and theoreticians alike.