超声引导的功能化细胞外囊泡用于可视化、控制和高效的肾脏递送，以增强肾脏修复（Adv. Healthcare Mater. 17/2025）

IF 10 2区医学 Q1 ENGINEERING, BIOMEDICAL

Advanced Healthcare Materials Pub Date : 2025-07-04 DOI:10.1002/adhm.202570100

Yuhao Chen, Chunjia Sheng, Tuo Xiao, Bo Jiang, Xieguanxuan Xu, Shaoyuan Cui, Wanjun Shen, Xumin Zheng, Xinru Guo, Xiangmei Chen, Chuyue Zhang, Guangyan Cai

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引用次数: 0

摘要

超声引导功能化细胞外囊泡在2404719中，张楚跃，蔡光岩等人开发了超声引导的细胞外囊泡，用于可视化和增强肾脏输送。通过增强f -肌动蛋白的恢复和促进摄取，这些工程载体克服了顺铂诱导的功能障碍。封面的灵感来自于中国的哪吒重生故事，象征着肾脏的再生就是哪吒的重生。神仙的力量，类似于“超声波暴露”，促进有效的内吞作用，使肾脏修复。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Ultrasound-Guided Functionalized Extracellular Vesicles for Visualized, Controlled, and Efficient Renal Delivery for Enhanced Kidney Repair (Adv. Healthcare Mater. 17/2025)

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Ultrasound-Guided Functionalized Extracellular Vesicles for Visualized, Controlled, and Efficient Renal Delivery for Enhanced Kidney Repair (Adv. Healthcare Mater. 17/2025)

Ultrasound-Guided Functionalized Extracellular Vesicles

In article 2404719, Chuyue Zhang, Guangyan Cai, and co-workers develop ultrasound-guided extracellular vesicles for visualized and enhanced renal delivery. By enhancing F-actin restoration and facilitating uptake, these engineered carriers overcome cisplatin-induced dysfunction. The cover is inspired by Chinese tale of Nezha's Rebirth, symbolizing kidney regeneration as Nezha's renewal. The immortal's power, akin to “ultrasound exposure,” promotes efficient endocytosis to enable kidney repair.

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来源期刊

Advanced Healthcare Materials 工程技术-生物材料

CiteScore

14.40

自引率

3.00%

发文量

600

审稿时长

1.8 months

期刊介绍： Advanced Healthcare Materials, a distinguished member of the esteemed Advanced portfolio, has been dedicated to disseminating cutting-edge research on materials, devices, and technologies for enhancing human well-being for over ten years. As a comprehensive journal, it encompasses a wide range of disciplines such as biomaterials, biointerfaces, nanomedicine and nanotechnology, tissue engineering, and regenerative medicine.