Yizhao Li , Adam Garry Redgrift , Takaaki Hiranaka , Alan Getgood , Ryan Willing
{"title":"模拟步态中内侧半月板后根撕裂和缝合锚修复后的接触力学:一项尸体研究","authors":"Yizhao Li , Adam Garry Redgrift , Takaaki Hiranaka , Alan Getgood , Ryan Willing","doi":"10.1016/j.jbiomech.2025.112837","DOIUrl":null,"url":null,"abstract":"<div><div>Medial Meniscus Posterior Root Tears (MMPRTs) are increasingly recognized, whereas research on contact mechanics associated with MMPRT during activities of daily living is limited. This study evaluated the effect of MMPRT on tibiofemoral pressure and the effectiveness of surgical repair during simulated gait. Eight fresh-frozen human cadaveric knees were tested using a joint motion simulator. Subject-specific loading profiles comprising seven key stages of the gait cycle were applied to (1) intact meniscus, (2) MMPRT, and (3) repair models. Contact pressure was measured at each stage using thin film pressure sensors beneath the menisci. The peak contact pressure (PCP), mean contact pressure (MCP), contact area (CA), and Dice similarity coefficient (DSC) that compares pressure distributions between conditions were evaluated. Compared to the intact condition, MMPRT caused significant differences in medial PCP, MCP, and CA, but only during the stance phase under the applied biomechanical model and loading conditions. Averaged across the stages within the stance phase, medial PCP and MPC were 32 % and 78 % higher, and CA was 35 % lower after MMPRT. After repair, these pressures generally remained significantly greater than their corresponding intact values. Specifically, medial PCP and MPC were on average 19 % and 40 % higher, and CA was 25 % lower than for the intact condition during the stance phase. DSCs relative to the intact state indicated that repair significantly improved pressure distributions (0.67–0.87) compared to MMPRT (0.47–0.78). The anatomic repair of MMPRT did not appear to fully restore intact contact pressure distributions in this study, suggesting that further improvement of surgical techniques may be beneficial.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"189 ","pages":"Article 112837"},"PeriodicalIF":2.4000,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Contact mechanics following medial meniscus posterior root tears and suture anchor repair in simulated gait: A cadaveric study\",\"authors\":\"Yizhao Li , Adam Garry Redgrift , Takaaki Hiranaka , Alan Getgood , Ryan Willing\",\"doi\":\"10.1016/j.jbiomech.2025.112837\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Medial Meniscus Posterior Root Tears (MMPRTs) are increasingly recognized, whereas research on contact mechanics associated with MMPRT during activities of daily living is limited. This study evaluated the effect of MMPRT on tibiofemoral pressure and the effectiveness of surgical repair during simulated gait. Eight fresh-frozen human cadaveric knees were tested using a joint motion simulator. Subject-specific loading profiles comprising seven key stages of the gait cycle were applied to (1) intact meniscus, (2) MMPRT, and (3) repair models. Contact pressure was measured at each stage using thin film pressure sensors beneath the menisci. The peak contact pressure (PCP), mean contact pressure (MCP), contact area (CA), and Dice similarity coefficient (DSC) that compares pressure distributions between conditions were evaluated. Compared to the intact condition, MMPRT caused significant differences in medial PCP, MCP, and CA, but only during the stance phase under the applied biomechanical model and loading conditions. Averaged across the stages within the stance phase, medial PCP and MPC were 32 % and 78 % higher, and CA was 35 % lower after MMPRT. After repair, these pressures generally remained significantly greater than their corresponding intact values. Specifically, medial PCP and MPC were on average 19 % and 40 % higher, and CA was 25 % lower than for the intact condition during the stance phase. DSCs relative to the intact state indicated that repair significantly improved pressure distributions (0.67–0.87) compared to MMPRT (0.47–0.78). The anatomic repair of MMPRT did not appear to fully restore intact contact pressure distributions in this study, suggesting that further improvement of surgical techniques may be beneficial.</div></div>\",\"PeriodicalId\":15168,\"journal\":{\"name\":\"Journal of biomechanics\",\"volume\":\"189 \",\"pages\":\"Article 112837\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-06-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of biomechanics\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0021929025003495\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"BIOPHYSICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomechanics","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0021929025003495","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOPHYSICS","Score":null,"Total":0}
Contact mechanics following medial meniscus posterior root tears and suture anchor repair in simulated gait: A cadaveric study
Medial Meniscus Posterior Root Tears (MMPRTs) are increasingly recognized, whereas research on contact mechanics associated with MMPRT during activities of daily living is limited. This study evaluated the effect of MMPRT on tibiofemoral pressure and the effectiveness of surgical repair during simulated gait. Eight fresh-frozen human cadaveric knees were tested using a joint motion simulator. Subject-specific loading profiles comprising seven key stages of the gait cycle were applied to (1) intact meniscus, (2) MMPRT, and (3) repair models. Contact pressure was measured at each stage using thin film pressure sensors beneath the menisci. The peak contact pressure (PCP), mean contact pressure (MCP), contact area (CA), and Dice similarity coefficient (DSC) that compares pressure distributions between conditions were evaluated. Compared to the intact condition, MMPRT caused significant differences in medial PCP, MCP, and CA, but only during the stance phase under the applied biomechanical model and loading conditions. Averaged across the stages within the stance phase, medial PCP and MPC were 32 % and 78 % higher, and CA was 35 % lower after MMPRT. After repair, these pressures generally remained significantly greater than their corresponding intact values. Specifically, medial PCP and MPC were on average 19 % and 40 % higher, and CA was 25 % lower than for the intact condition during the stance phase. DSCs relative to the intact state indicated that repair significantly improved pressure distributions (0.67–0.87) compared to MMPRT (0.47–0.78). The anatomic repair of MMPRT did not appear to fully restore intact contact pressure distributions in this study, suggesting that further improvement of surgical techniques may be beneficial.
期刊介绍:
The Journal of Biomechanics publishes reports of original and substantial findings using the principles of mechanics to explore biological problems. Analytical, as well as experimental papers may be submitted, and the journal accepts original articles, surveys and perspective articles (usually by Editorial invitation only), book reviews and letters to the Editor. The criteria for acceptance of manuscripts include excellence, novelty, significance, clarity, conciseness and interest to the readership.
Papers published in the journal may cover a wide range of topics in biomechanics, including, but not limited to:
-Fundamental Topics - Biomechanics of the musculoskeletal, cardiovascular, and respiratory systems, mechanics of hard and soft tissues, biofluid mechanics, mechanics of prostheses and implant-tissue interfaces, mechanics of cells.
-Cardiovascular and Respiratory Biomechanics - Mechanics of blood-flow, air-flow, mechanics of the soft tissues, flow-tissue or flow-prosthesis interactions.
-Cell Biomechanics - Biomechanic analyses of cells, membranes and sub-cellular structures; the relationship of the mechanical environment to cell and tissue response.
-Dental Biomechanics - Design and analysis of dental tissues and prostheses, mechanics of chewing.
-Functional Tissue Engineering - The role of biomechanical factors in engineered tissue replacements and regenerative medicine.
-Injury Biomechanics - Mechanics of impact and trauma, dynamics of man-machine interaction.
-Molecular Biomechanics - Mechanical analyses of biomolecules.
-Orthopedic Biomechanics - Mechanics of fracture and fracture fixation, mechanics of implants and implant fixation, mechanics of bones and joints, wear of natural and artificial joints.
-Rehabilitation Biomechanics - Analyses of gait, mechanics of prosthetics and orthotics.
-Sports Biomechanics - Mechanical analyses of sports performance.