模拟步态中内侧半月板后根撕裂和缝合锚修复后的接触力学:一项尸体研究

IF 2.4 3区 医学 Q3 BIOPHYSICS
Yizhao Li , Adam Garry Redgrift , Takaaki Hiranaka , Alan Getgood , Ryan Willing
{"title":"模拟步态中内侧半月板后根撕裂和缝合锚修复后的接触力学:一项尸体研究","authors":"Yizhao Li ,&nbsp;Adam Garry Redgrift ,&nbsp;Takaaki Hiranaka ,&nbsp;Alan Getgood ,&nbsp;Ryan Willing","doi":"10.1016/j.jbiomech.2025.112837","DOIUrl":null,"url":null,"abstract":"<div><div>Medial Meniscus Posterior Root Tears (MMPRTs) are increasingly recognized, whereas research on contact mechanics associated with MMPRT during activities of daily living is limited. This study evaluated the effect of MMPRT on tibiofemoral pressure and the effectiveness of surgical repair during simulated gait. Eight fresh-frozen human cadaveric knees were tested using a joint motion simulator. Subject-specific loading profiles comprising seven key stages of the gait cycle were applied to (1) intact meniscus, (2) MMPRT, and (3) repair models. Contact pressure was measured at each stage using thin film pressure sensors beneath the menisci. The peak contact pressure (PCP), mean contact pressure (MCP), contact area (CA), and Dice similarity coefficient (DSC) that compares pressure distributions between conditions were evaluated. Compared to the intact condition, MMPRT caused significant differences in medial PCP, MCP, and CA, but only during the stance phase under the applied biomechanical model and loading conditions. Averaged across the stages within the stance phase, medial PCP and MPC were 32 % and 78 % higher, and CA was 35 % lower after MMPRT. After repair, these pressures generally remained significantly greater than their corresponding intact values. Specifically, medial PCP and MPC were on average 19 % and 40 % higher, and CA was 25 % lower than for the intact condition during the stance phase. DSCs relative to the intact state indicated that repair significantly improved pressure distributions (0.67–0.87) compared to MMPRT (0.47–0.78). The anatomic repair of MMPRT did not appear to fully restore intact contact pressure distributions in this study, suggesting that further improvement of surgical techniques may be beneficial.</div></div>","PeriodicalId":15168,"journal":{"name":"Journal of biomechanics","volume":"189 ","pages":"Article 112837"},"PeriodicalIF":2.4000,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Contact mechanics following medial meniscus posterior root tears and suture anchor repair in simulated gait: A cadaveric study\",\"authors\":\"Yizhao Li ,&nbsp;Adam Garry Redgrift ,&nbsp;Takaaki Hiranaka ,&nbsp;Alan Getgood ,&nbsp;Ryan Willing\",\"doi\":\"10.1016/j.jbiomech.2025.112837\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Medial Meniscus Posterior Root Tears (MMPRTs) are increasingly recognized, whereas research on contact mechanics associated with MMPRT during activities of daily living is limited. This study evaluated the effect of MMPRT on tibiofemoral pressure and the effectiveness of surgical repair during simulated gait. Eight fresh-frozen human cadaveric knees were tested using a joint motion simulator. Subject-specific loading profiles comprising seven key stages of the gait cycle were applied to (1) intact meniscus, (2) MMPRT, and (3) repair models. Contact pressure was measured at each stage using thin film pressure sensors beneath the menisci. The peak contact pressure (PCP), mean contact pressure (MCP), contact area (CA), and Dice similarity coefficient (DSC) that compares pressure distributions between conditions were evaluated. Compared to the intact condition, MMPRT caused significant differences in medial PCP, MCP, and CA, but only during the stance phase under the applied biomechanical model and loading conditions. Averaged across the stages within the stance phase, medial PCP and MPC were 32 % and 78 % higher, and CA was 35 % lower after MMPRT. After repair, these pressures generally remained significantly greater than their corresponding intact values. Specifically, medial PCP and MPC were on average 19 % and 40 % higher, and CA was 25 % lower than for the intact condition during the stance phase. DSCs relative to the intact state indicated that repair significantly improved pressure distributions (0.67–0.87) compared to MMPRT (0.47–0.78). The anatomic repair of MMPRT did not appear to fully restore intact contact pressure distributions in this study, suggesting that further improvement of surgical techniques may be beneficial.</div></div>\",\"PeriodicalId\":15168,\"journal\":{\"name\":\"Journal of biomechanics\",\"volume\":\"189 \",\"pages\":\"Article 112837\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-06-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of biomechanics\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0021929025003495\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"BIOPHYSICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of biomechanics","FirstCategoryId":"5","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0021929025003495","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"BIOPHYSICS","Score":null,"Total":0}
引用次数: 0

摘要

内侧半月板后根撕裂(MMPRTs)越来越被人们所认识,然而在日常生活活动中与MMPRT相关的接触力学研究却很有限。本研究评估了MMPRT在模拟步态下对胫股压力的影响以及手术修复的有效性。使用关节运动模拟器对8个新鲜冷冻的人体尸体膝盖进行了测试。包括步态周期七个关键阶段的受试者特定负荷谱应用于(1)完整半月板,(2)MMPRT和(3)修复模型。使用半月板下的薄膜压力传感器测量每个阶段的接触压力。评估了峰值接触压力(PCP)、平均接触压力(MCP)、接触面积(CA)和比较不同条件下压力分布的Dice相似系数(DSC)。在应用生物力学模型和加载条件下,与完整条件相比,MMPRT引起内侧PCP、MCP和CA的显著差异,但仅在站立阶段。在站立期各阶段的平均水平上,MMPRT后内侧PCP和MPC分别升高32%和78%,CA降低35%。修复后,这些压力通常仍然明显大于相应的完整值。具体来说,在站立阶段,内侧PCP和MPC比完整状态平均高出19%和40%,CA比完整状态低25%。相对于完整状态的dsc,与MMPRT(0.47-0.78)相比,修复后的压力分布显著改善(0.67-0.87)。在本研究中,MMPRT的解剖修复似乎没有完全恢复完整的接触压力分布,这表明进一步改进手术技术可能是有益的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Contact mechanics following medial meniscus posterior root tears and suture anchor repair in simulated gait: A cadaveric study
Medial Meniscus Posterior Root Tears (MMPRTs) are increasingly recognized, whereas research on contact mechanics associated with MMPRT during activities of daily living is limited. This study evaluated the effect of MMPRT on tibiofemoral pressure and the effectiveness of surgical repair during simulated gait. Eight fresh-frozen human cadaveric knees were tested using a joint motion simulator. Subject-specific loading profiles comprising seven key stages of the gait cycle were applied to (1) intact meniscus, (2) MMPRT, and (3) repair models. Contact pressure was measured at each stage using thin film pressure sensors beneath the menisci. The peak contact pressure (PCP), mean contact pressure (MCP), contact area (CA), and Dice similarity coefficient (DSC) that compares pressure distributions between conditions were evaluated. Compared to the intact condition, MMPRT caused significant differences in medial PCP, MCP, and CA, but only during the stance phase under the applied biomechanical model and loading conditions. Averaged across the stages within the stance phase, medial PCP and MPC were 32 % and 78 % higher, and CA was 35 % lower after MMPRT. After repair, these pressures generally remained significantly greater than their corresponding intact values. Specifically, medial PCP and MPC were on average 19 % and 40 % higher, and CA was 25 % lower than for the intact condition during the stance phase. DSCs relative to the intact state indicated that repair significantly improved pressure distributions (0.67–0.87) compared to MMPRT (0.47–0.78). The anatomic repair of MMPRT did not appear to fully restore intact contact pressure distributions in this study, suggesting that further improvement of surgical techniques may be beneficial.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of biomechanics
Journal of biomechanics 生物-工程:生物医学
CiteScore
5.10
自引率
4.20%
发文量
345
审稿时长
1 months
期刊介绍: The Journal of Biomechanics publishes reports of original and substantial findings using the principles of mechanics to explore biological problems. Analytical, as well as experimental papers may be submitted, and the journal accepts original articles, surveys and perspective articles (usually by Editorial invitation only), book reviews and letters to the Editor. The criteria for acceptance of manuscripts include excellence, novelty, significance, clarity, conciseness and interest to the readership. Papers published in the journal may cover a wide range of topics in biomechanics, including, but not limited to: -Fundamental Topics - Biomechanics of the musculoskeletal, cardiovascular, and respiratory systems, mechanics of hard and soft tissues, biofluid mechanics, mechanics of prostheses and implant-tissue interfaces, mechanics of cells. -Cardiovascular and Respiratory Biomechanics - Mechanics of blood-flow, air-flow, mechanics of the soft tissues, flow-tissue or flow-prosthesis interactions. -Cell Biomechanics - Biomechanic analyses of cells, membranes and sub-cellular structures; the relationship of the mechanical environment to cell and tissue response. -Dental Biomechanics - Design and analysis of dental tissues and prostheses, mechanics of chewing. -Functional Tissue Engineering - The role of biomechanical factors in engineered tissue replacements and regenerative medicine. -Injury Biomechanics - Mechanics of impact and trauma, dynamics of man-machine interaction. -Molecular Biomechanics - Mechanical analyses of biomolecules. -Orthopedic Biomechanics - Mechanics of fracture and fracture fixation, mechanics of implants and implant fixation, mechanics of bones and joints, wear of natural and artificial joints. -Rehabilitation Biomechanics - Analyses of gait, mechanics of prosthetics and orthotics. -Sports Biomechanics - Mechanical analyses of sports performance.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信