Dai Hao-Yu, Cao Yi-Wei, Li Shao-Ke, Lin Dong-Liang, Lin Cun-Zhi, Xiao Bao-Hong
{"title":"结外NK/ t细胞淋巴瘤误诊为肺部感染。","authors":"Dai Hao-Yu, Cao Yi-Wei, Li Shao-Ke, Lin Dong-Liang, Lin Cun-Zhi, Xiao Bao-Hong","doi":"10.46883/2025.25921043","DOIUrl":null,"url":null,"abstract":"<p><p>Extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is highly invasive. Its etiology and pathogenesis may be related to Epstein-Barr virus infection. In this article, we report a case of a man with ENKTL affecting the right vocal cord and right lung. Initially, the lesion was misdiagnosed as a pulmonary infection. However, subsequent histopathological examinations confirmed the diagnosis through analysis of a surgically resected specimen. Following 14 cycles of immune therapy and chemotherapy, the lesion in the right lung significantly shrank. This case underscored the importance of obtaining surgically resected specimens for pathology when ENKTL is suspected, which can improve diagnostic accuracy and mitigate misdiagnosis.</p>","PeriodicalId":51147,"journal":{"name":"Oncology-New York","volume":"null 5","pages":"198-203"},"PeriodicalIF":1.8000,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Extranodal NK/T-Cell Lymphoma Misdiagnosed as Pulmonary Infection.\",\"authors\":\"Dai Hao-Yu, Cao Yi-Wei, Li Shao-Ke, Lin Dong-Liang, Lin Cun-Zhi, Xiao Bao-Hong\",\"doi\":\"10.46883/2025.25921043\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is highly invasive. Its etiology and pathogenesis may be related to Epstein-Barr virus infection. In this article, we report a case of a man with ENKTL affecting the right vocal cord and right lung. Initially, the lesion was misdiagnosed as a pulmonary infection. However, subsequent histopathological examinations confirmed the diagnosis through analysis of a surgically resected specimen. Following 14 cycles of immune therapy and chemotherapy, the lesion in the right lung significantly shrank. This case underscored the importance of obtaining surgically resected specimens for pathology when ENKTL is suspected, which can improve diagnostic accuracy and mitigate misdiagnosis.</p>\",\"PeriodicalId\":51147,\"journal\":{\"name\":\"Oncology-New York\",\"volume\":\"null 5\",\"pages\":\"198-203\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-06-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Oncology-New York\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.46883/2025.25921043\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"ONCOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Oncology-New York","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.46883/2025.25921043","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ONCOLOGY","Score":null,"Total":0}
Extranodal NK/T-Cell Lymphoma Misdiagnosed as Pulmonary Infection.
Extranodal natural killer (NK)/T-cell lymphoma (ENKTL) is highly invasive. Its etiology and pathogenesis may be related to Epstein-Barr virus infection. In this article, we report a case of a man with ENKTL affecting the right vocal cord and right lung. Initially, the lesion was misdiagnosed as a pulmonary infection. However, subsequent histopathological examinations confirmed the diagnosis through analysis of a surgically resected specimen. Following 14 cycles of immune therapy and chemotherapy, the lesion in the right lung significantly shrank. This case underscored the importance of obtaining surgically resected specimens for pathology when ENKTL is suspected, which can improve diagnostic accuracy and mitigate misdiagnosis.
期刊介绍:
Although laboratory and clinical cancer research need to be closely linked, observations at the basic level often remain removed from medical applications. This journal works to accelerate the translation of experimental results into the clinic, and back again into the laboratory for further investigation. The fundamental purpose of this effort is to advance clinically-relevant knowledge of cancer, and improve the outcome of prevention, diagnosis and treatment of malignant disease. The journal publishes significant clinical studies from cancer programs around the world, along with important translational laboratory findings, mini-reviews (invited and submitted) and in-depth discussions of evolving and controversial topics in the oncology arena. A unique feature of the journal is a new section which focuses on rapid peer-review and subsequent publication of short reports of phase 1 and phase 2 clinical cancer trials, with a goal of insuring that high-quality clinical cancer research quickly enters the public domain, regardless of the trial’s ultimate conclusions regarding efficacy or toxicity.