Dario Angelone, Noreen Nudds, Andrew B Matheson, Ahmet T Erdogan, Walter Messina, Ray Burke, Robert K Henderson, Stefan Andersson-Engels, Sanathana Konugolu Venkata Sekar
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We present a chip-on-tip fluorescence lifetime imaging micro-camera on a size scale compatible with endoscopic applications. The micro-camera has an external diameter of 4 mm and comprises a miniaturized 128 × 120 SPAD array detector, integrated imaging optics, and an optical fiber for excitation light delivery. The spatial performance is characterized by imaging a resolution test target showing that the integrated system is able to resolve features of <30μm. The temporal response is measured at a range of wavelengths, yielding a mean pixel impulse response width of < 1 ns. Benchmarking against a time-correlated single-photon counting system also shows good agreement with the micro-camera. Finally, fluorescence lifetime images of unlabeled ex vivo animal tissue samples are presented as examples.
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The Optical Society (OSA) publishes high-quality, peer-reviewed articles in its portfolio of journals, which serve the full breadth of the optics and photonics community.
Optics Letters offers rapid dissemination of new results in all areas of optics with short, original, peer-reviewed communications. Optics Letters covers the latest research in optical science, including optical measurements, optical components and devices, atmospheric optics, biomedical optics, Fourier optics, integrated optics, optical processing, optoelectronics, lasers, nonlinear optics, optical storage and holography, optical coherence, polarization, quantum electronics, ultrafast optical phenomena, photonic crystals, and fiber optics. Criteria used in determining acceptability of contributions include newsworthiness to a substantial part of the optics community and the effect of rapid publication on the research of others. This journal, published twice each month, is where readers look for the latest discoveries in optics.
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