Rares-Adrian Giurgiu, Catalina-Stefania Dumitru, Andreea Grosu-Bularda, Eliza-Maria Bordeanu-Diaconescu, Adrian Frunza, Sabina Grama, Florin-Vlad Hodea, Tiberiu-Paul Neagu, Ioan Lascar, Cristian-Sorin Hariga
{"title":"化学烧伤:病理生理学和治疗方案-颈部-面部损伤会带来特殊的挑战吗?","authors":"Rares-Adrian Giurgiu, Catalina-Stefania Dumitru, Andreea Grosu-Bularda, Eliza-Maria Bordeanu-Diaconescu, Adrian Frunza, Sabina Grama, Florin-Vlad Hodea, Tiberiu-Paul Neagu, Ioan Lascar, Cristian-Sorin Hariga","doi":"10.25122/jml-2025-0082","DOIUrl":null,"url":null,"abstract":"<p><p>Chemical burns, though relatively rare, present significant diagnostic and therapeutic challenges due to their complex pathophysiology and the need for specialized care. A retrospective study was conducted, examining the characteristics, treatment, and outcomes of 33 patients with chemical burns admitted to our burn center for 8 years, representing 4.39% of all burn cases. Among them, 15 patients (45.45%) had chemical burns on the face and neck. The majority of these patients were men, with a relatively younger average age, and a significant proportion had work-related accidents. The burned surface area was variable, with many patients sustaining small total body surface area (TBSA), although some presented with extensive involvement. The prevalence of superficial partial-thickness burns was higher, but deep partial-thickness and full-thickness burns were also common. A large proportion of patients had favorable Abbreviated Burn Severity Index (ABSI) scores, indicating a high probability of survival. However, ocular involvement was a major complication. The study emphasizes the importance of timely intervention, including appropriate wound management strategies, specialized dressings, and skin substitutes. The findings also stress the need for a multidisciplinary approach, close monitoring, and adherence to safety protocols to optimize outcomes and minimize long-term complications in patients with chemical burns, particularly those of the face and neck region.</p>","PeriodicalId":16386,"journal":{"name":"Journal of Medicine and Life","volume":"18 5","pages":"440-448"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207703/pdf/","citationCount":"0","resultStr":"{\"title\":\"Chemical burns: pathophysiology and therapeutic protocols-do cervico-facial injuries pose specific challenges?\",\"authors\":\"Rares-Adrian Giurgiu, Catalina-Stefania Dumitru, Andreea Grosu-Bularda, Eliza-Maria Bordeanu-Diaconescu, Adrian Frunza, Sabina Grama, Florin-Vlad Hodea, Tiberiu-Paul Neagu, Ioan Lascar, Cristian-Sorin Hariga\",\"doi\":\"10.25122/jml-2025-0082\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Chemical burns, though relatively rare, present significant diagnostic and therapeutic challenges due to their complex pathophysiology and the need for specialized care. A retrospective study was conducted, examining the characteristics, treatment, and outcomes of 33 patients with chemical burns admitted to our burn center for 8 years, representing 4.39% of all burn cases. Among them, 15 patients (45.45%) had chemical burns on the face and neck. The majority of these patients were men, with a relatively younger average age, and a significant proportion had work-related accidents. The burned surface area was variable, with many patients sustaining small total body surface area (TBSA), although some presented with extensive involvement. The prevalence of superficial partial-thickness burns was higher, but deep partial-thickness and full-thickness burns were also common. A large proportion of patients had favorable Abbreviated Burn Severity Index (ABSI) scores, indicating a high probability of survival. However, ocular involvement was a major complication. The study emphasizes the importance of timely intervention, including appropriate wound management strategies, specialized dressings, and skin substitutes. The findings also stress the need for a multidisciplinary approach, close monitoring, and adherence to safety protocols to optimize outcomes and minimize long-term complications in patients with chemical burns, particularly those of the face and neck region.</p>\",\"PeriodicalId\":16386,\"journal\":{\"name\":\"Journal of Medicine and Life\",\"volume\":\"18 5\",\"pages\":\"440-448\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12207703/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medicine and Life\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25122/jml-2025-0082\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medicine and Life","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25122/jml-2025-0082","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Chemical burns: pathophysiology and therapeutic protocols-do cervico-facial injuries pose specific challenges?
Chemical burns, though relatively rare, present significant diagnostic and therapeutic challenges due to their complex pathophysiology and the need for specialized care. A retrospective study was conducted, examining the characteristics, treatment, and outcomes of 33 patients with chemical burns admitted to our burn center for 8 years, representing 4.39% of all burn cases. Among them, 15 patients (45.45%) had chemical burns on the face and neck. The majority of these patients were men, with a relatively younger average age, and a significant proportion had work-related accidents. The burned surface area was variable, with many patients sustaining small total body surface area (TBSA), although some presented with extensive involvement. The prevalence of superficial partial-thickness burns was higher, but deep partial-thickness and full-thickness burns were also common. A large proportion of patients had favorable Abbreviated Burn Severity Index (ABSI) scores, indicating a high probability of survival. However, ocular involvement was a major complication. The study emphasizes the importance of timely intervention, including appropriate wound management strategies, specialized dressings, and skin substitutes. The findings also stress the need for a multidisciplinary approach, close monitoring, and adherence to safety protocols to optimize outcomes and minimize long-term complications in patients with chemical burns, particularly those of the face and neck region.
期刊介绍:
The Journal of Medicine and Life publishes peer-reviewed articles from various fields of medicine and life sciences, including original research, systematic reviews, special reports, case presentations, major medical breakthroughs and letters to the editor. The Journal focuses on current matters that lie at the intersection of biomedical science and clinical practice and strives to present this information to inform health care delivery and improve patient outcomes. Papers addressing topics such as neuroprotection, neurorehabilitation, neuroplasticity, and neuroregeneration are particularly encouraged, as part of the Journal''s continuous interest in neuroscience research. The Editorial Board of the Journal of Medicine and Life is open to consider manuscripts from all levels of research and areas of biological sciences, including fundamental, experimental or clinical research and matters of public health. As part of our pledge to promote an educational and community-building environment, our issues feature sections designated to informing our readers regarding exciting international congresses, teaching courses and relevant institutional-level events.