氟哌啶醇意外不良反应:精神分裂症患者急性舌血管性水肿病例报告与回顾。

Q4 Medicine
Case Reports in Psychiatry Pub Date : 2025-06-24 eCollection Date: 2025-01-01 DOI:10.1155/crps/4133014
Nadia Romdhane, Dorra Chiboub, Ameni Amri, Asma Ayedi, Emna Rejeb, Imen Zoghlami, Safa Nefzaoui, Ines Hariga, Chiraz Mbarek
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引用次数: 0

摘要

舌血管性水肿,又称血管神经性水肿或奎克水肿,是由于血浆从毛细血管和毛细血管后小静脉渗漏到深部粘膜下组织而引起的舌肿胀。这种情况可能是遗传性的,也可能是后天的,比如由于过敏引起的反应。急性发作时,由于突然和完全的上呼吸道阻塞,这种现象可能会危及生命。我们的目的是描述一个54岁的精神分裂症男性患者,他在口服氟哌啶醇(第一代抗精神病药)后出现舌血管性水肿。患者入院接受密切呼吸监测。这种情况的确定原因是氟哌啶醇过敏反应。接下来的疗程是一个很好的结果,水肿完全消失,没有呼吸窘迫。我们的目标是报告我们的病例,并深入研究到目前为止在文献中报道的其他现有的类似病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Unexpected Adverse Effect of Haloperidol: Acute Tongue Angioedema in a Schizophrenic Patient-Case Report and Review.

Angioedema of the tongue, also known as angioneurotic, or Quinke edema is a swelling of the tongue due to plasma leaking from capillary and postcapillary venules into deep submucosal tissue. This condition can either be hereditary, or acquired, due to allergy induced reactions for example. With an acute onset, this phenomenon can potentially be life threatening due to sudden and complete upper airway obstruction. Our aim is to describe the case of a 54-year-old schizophrenic male patient who presented with an angioedema of the tongue occurring after oral administration of haloperidol, a first-generation antipsychotic. The patient was admitted for close respiratory monitoring. The established cause for this condition was an allergic reaction to haloperidol. The following course was a favorable outcome with complete resolution of the edema without respiratory distress. We aim to report our case and to delve into other existing similar cases reported thus far in literature.

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来源期刊
Case Reports in Psychiatry
Case Reports in Psychiatry Medicine-Psychiatry and Mental Health
CiteScore
1.00
自引率
0.00%
发文量
49
审稿时长
12 weeks
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