孟加拉国三级医院甲状腺全切除术后甲状旁腺功能减退的发病率

Mymensingh medical journal : MMJ Pub Date : 2025-07-01
M Ahmed, M A Siddique, M M Islam, M Nuruzzaman, M M Alam, M J A Khan
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摘要

甲状腺全切除术是MNG和甲状腺恶性肿瘤伴或不伴淋巴结转移的常见手术方法。甲状腺全切除术后甲状旁腺功能减退并不少见。了解甲状腺全切除术后暂时性和永久性甲状旁腺功能减退的患病率对改善患者预后非常重要。这项前瞻性观察研究于2023年1月至2023年12月在孟加拉国Mymensingh医学院医院进行,有目的地选择了92例因MNG和甲状腺恶性肿瘤而行全甲状腺切除术的患者,没有额外的甲状腺延伸。分析全甲状腺切除术后短暂性和永久性甲状旁腺功能减退的发生率、人口统计学变量和术后低钙发病天数。数据收集通过患者记录和术后随访完成。本研究显示23.0%的患者术后出现甲状旁腺功能减退。甲状旁腺功能低下在因甲状腺恶性肿瘤行全甲状腺切除术的患者中最为常见(47.83%),而在因甲状腺良性疾病行全甲状腺切除术的患者中发病率仅为17.39%。低血钙发生率最高(60.87%)发生在术后第2天。术后23例甲状旁腺功能减退患者中,暂时性甲状旁腺功能减退占69.57%,永久性甲状旁腺功能减退占30.43%。甲状腺全切除术后甲状旁腺功能减退仍然是一个重要的并发症。早期识别和管理高危患者对于降低这种并发症的严重程度是必要的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Incidence of Hypoparathyroidism Following Total Thyroidectomy in a Tertiary Care Hospital of Bangladesh.

Total thyroidectomy is a common surgical procedure for MNG and thyroid malignancies with or without lymph node metastasis. Post total thyroidectomy hypoparathyroidism is not so uncommon. Understanding the prevalence of temporary and permanent hypoparathyroidism in post-total thyroidectomy is very important for improving patient outcomes. This prospective observational study was conducted in Mymensingh Medical College Hospital, Mymensingh, Bangladesh from January 2023 to December 2023 where 92 cases were selected purposively who underwent total thyroidectomy for MNG and thyroid malignancy without extra thyroidal extension. The incidence of transient and permanent hypoparathyroidism after total thyroidectomy, demographic variables, and postoperative day of onset of hypocalcemia were analyzed. Data collection was done through patient records and postoperative follow-ups. This study revealed that 23.0% of patients experienced hypoparathyroidism post-operatively. Hypoparathyroidism was most prevalent among patients underwent total thyroidectomy for thyroid malignancy (47.83%) compared to those undergoing total thyroidectomy for benign thyroid disease (17.39%). The majority of hypocalcemia cases (60.87%) occurred on the second postoperative day. Among the 23 cases of postoperative hypoparathyroidism temporary hypoparathyroidism was 69.57% and permanent hypoparathyroidism was 30.43%. After total thyroidectomy Hypoparathyroidism remains a significant complication. Early identification and management of at-risk patients is necessary to reduce the severity of this complication.

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