聚乙二醇化W4.6N4/WO3纳米颗粒作为近红外光热剂用于有效的癌症治疗。

IF 6.1 3区 医学 Q1 MATERIALS SCIENCE, BIOMATERIALS
Rui Yang, Jianping Li, Hao Song, Cong Wang and Na Xu
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引用次数: 0

摘要

近年来,具有良好光热转换效率的近红外(NIR)光敏光热剂(PTAs)在提高先进光热治疗(PTT)性能方面显示出巨大潜力。本研究设计并构建了具有异质结结构的聚乙二醇修饰的氮化钨/氧化钨纳米粒子(聚乙二醇化的W4.6N4/WO3-NPs)。聚乙二醇化的W4.6N4/WO3-NPs在808 nm辐照下具有较强的近红外窗口吸收能力和光热转换能力。聚乙二醇化的W4.6N4/WO3-NPs具有良好的生物相容性和有效的肿瘤消融功能。因此,聚乙二醇化的W4.6N4/WO3-NPs可以用作光热剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

PEGylated W4.6N4/WO3 nanoparticles as a near-infrared photothermal agent for effective cancer therapy†

PEGylated W4.6N4/WO3 nanoparticles as a near-infrared photothermal agent for effective cancer therapy†

In recent years, near-infrared (NIR) light-sensitive photothermal agents (PTAs) with excellent photothermal conversion efficiency have shown great potential in enhancing the performance of advanced photothermal therapy (PTT). In this study, polyethylene glycol (PEG)-modified tungsten nitride/tungsten oxide nanoparticles (PEGylated W4.6N4/WO3-NPs) with heterojunction structures were designed and constructed. The PEGylated W4.6N4/WO3-NPs showed strong absorbance ability in the NIR window and photothermal conversion under 808 nm irradiation. The PEGylated W4.6N4/WO3-NPs exhibited good biocompatibility and efficient tumor ablation function. Therefore, the PEGylated W4.6N4/WO3-NPs can be used as a photothermal agent.

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来源期刊
Journal of Materials Chemistry B
Journal of Materials Chemistry B MATERIALS SCIENCE, BIOMATERIALS-
CiteScore
11.50
自引率
4.30%
发文量
866
期刊介绍: Journal of Materials Chemistry A, B & C cover high quality studies across all fields of materials chemistry. The journals focus on those theoretical or experimental studies that report new understanding, applications, properties and synthesis of materials. Journal of Materials Chemistry A, B & C are separated by the intended application of the material studied. Broadly, applications in energy and sustainability are of interest to Journal of Materials Chemistry A, applications in biology and medicine are of interest to Journal of Materials Chemistry B, and applications in optical, magnetic and electronic devices are of interest to Journal of Materials Chemistry C.Journal of Materials Chemistry B is a Transformative Journal and Plan S compliant. Example topic areas within the scope of Journal of Materials Chemistry B are listed below. This list is neither exhaustive nor exclusive: Antifouling coatings Biocompatible materials Bioelectronics Bioimaging Biomimetics Biomineralisation Bionics Biosensors Diagnostics Drug delivery Gene delivery Immunobiology Nanomedicine Regenerative medicine & Tissue engineering Scaffolds Soft robotics Stem cells Therapeutic devices
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