{"title":"阿普米司特治疗掌足底嗜酸性脓疱性毛囊炎1例。","authors":"Jing Xu, Yue-Meng Wu, Shang-Shang Wang","doi":"10.1093/skinhd/vzaf019","DOIUrl":null,"url":null,"abstract":"<p><p>Eosinophilic pustular folliculitis (EPF) is a rare inflammatory dermatosis that predominantly affects seborrheic areas. The condition's pathogenesis is linked to T helper 2-driven eosinophilic inflammation. We presented a man with EPF involving the face, palms and soles, successfully treated by apremilast, a phosphodiesterase-4 inhibitor. Apremilast's efficacy in this case adds to emerging evidence supporting its use in EPF, particularly when traditional treatments fail.</p>","PeriodicalId":74804,"journal":{"name":"Skin health and disease","volume":"5 3","pages":"223-226"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202859/pdf/","citationCount":"0","resultStr":"{\"title\":\"A case of eosinophilic pustular folliculitis involving palmoplantar successfully treated by apremilast.\",\"authors\":\"Jing Xu, Yue-Meng Wu, Shang-Shang Wang\",\"doi\":\"10.1093/skinhd/vzaf019\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Eosinophilic pustular folliculitis (EPF) is a rare inflammatory dermatosis that predominantly affects seborrheic areas. The condition's pathogenesis is linked to T helper 2-driven eosinophilic inflammation. We presented a man with EPF involving the face, palms and soles, successfully treated by apremilast, a phosphodiesterase-4 inhibitor. Apremilast's efficacy in this case adds to emerging evidence supporting its use in EPF, particularly when traditional treatments fail.</p>\",\"PeriodicalId\":74804,\"journal\":{\"name\":\"Skin health and disease\",\"volume\":\"5 3\",\"pages\":\"223-226\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-04-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12202859/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Skin health and disease\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/skinhd/vzaf019\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/6/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Skin health and disease","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/skinhd/vzaf019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
A case of eosinophilic pustular folliculitis involving palmoplantar successfully treated by apremilast.
Eosinophilic pustular folliculitis (EPF) is a rare inflammatory dermatosis that predominantly affects seborrheic areas. The condition's pathogenesis is linked to T helper 2-driven eosinophilic inflammation. We presented a man with EPF involving the face, palms and soles, successfully treated by apremilast, a phosphodiesterase-4 inhibitor. Apremilast's efficacy in this case adds to emerging evidence supporting its use in EPF, particularly when traditional treatments fail.
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