我们应该在器官分配中使用行为预测吗?

IF 1.7 2区 哲学 Q2 ETHICS
Bioethics Pub Date : 2025-06-29 DOI:10.1111/bioe.13440
Max Drezga-Kleiminger, Dominic Wilkinson, Thomas Douglas, Joanna Demaree-Cotton, Julian Koplin, Julian Savulescu
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引用次数: 0

摘要

例如,关于病人生存可能性的医学预测可用于有效分配稀缺资源。对患者行为的预测也可以使用——例如,肝移植等待名单上的患者可能会因为不遵守免疫抑制药物治疗方案或过度饮酒的可能性而获得较低的优先级。但这在道德上可以接受吗?在本文中,我们将探讨支持和反对行为预测的论点,然后为这个问题提供新的经验证据。首先,我们注意到,包括行为预测将导致移植结果的改善。公平还可能要求优先考虑那些被预测会从事更健康行为的人:这与在精神病学和药物滥用等其他情况下使用行为预测是一致的。相反,行为预测可能被认为过于不准确或具有歧视性,或者可能被认为是不公平的。在第二部分中,我们对172名英国成年人进行了在线调查。当提出与肝脏分配相关的可能因素时,大多数人认为应该使用更高的药物依从性(78.6%)和更低的未来酒精使用(76.5%),而不是更低的未来犯罪(24.7%)和更高的社会贡献(21.2%)。将参与者随机分为两组,69.8%的参与者认为根据预测的药物依从性来降低患者的优先级是可以接受的(91.9%的参与者认为非行为预测是可以接受的)。我们没有发现行为预测和其他已经用于器官分配的医学预测之间存在伦理上的差异。我们的参与者样本似乎也支持这种情况下的行为预测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Should We Use Behavioural Predictions in Organ Allocation?

Medical predictions, for example, concerning a patient's likelihood of survival, can be used to efficiently allocate scarce resources. Predictions of patient behaviour can also be used-for example, patients on the liver transplant waiting list could receive lower priority based on a high likelihood of non-adherence to their immunosuppressant medication regimen or of drinking excessively. But is this ethically acceptable? In this paper, we will explore arguments for and against behavioural predictions, before providing novel empirical evidence on this question. Firstly, we note that including behavioural predictions would lead to improved transplant outcomes. Fairness could also require prioritising those predicted to engage in healthier behaviours: consistent with using behavioural predictions in other contexts such as psychiatry and substance misuse. Conversely, behavioural predictions may be judged too inaccurate or discriminatory, or it may be thought unfair to deprioritise based on future behaviour. In part two, we performed an online survey of 172 UK adults. When presented with possible factors relevant to liver allocation, most thought predictions of higher medication adherence (78.6%) and lower future alcohol use (76.5%) should be used but not predictions of lower future criminality (24.7%) and higher societal contribution (21.2%). Randomising participants into two groups, 69.8% of participants found deprioritising a patient based on their predicted medication adherence acceptable (91.9% found a nonbehavioural prediction acceptable). We did not identify an ethically relevant difference between behavioural predictions and other medical predictions already used in organ allocation. Our sample of participants also appeared to support behavioural predictions in this context.

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来源期刊
Bioethics
Bioethics 医学-医学:伦理
CiteScore
4.20
自引率
9.10%
发文量
127
审稿时长
6-12 weeks
期刊介绍: As medical technology continues to develop, the subject of bioethics has an ever increasing practical relevance for all those working in philosophy, medicine, law, sociology, public policy, education and related fields. Bioethics provides a forum for well-argued articles on the ethical questions raised by current issues such as: international collaborative clinical research in developing countries; public health; infectious disease; AIDS; managed care; genomics and stem cell research. These questions are considered in relation to concrete ethical, legal and policy problems, or in terms of the fundamental concepts, principles and theories used in discussions of such problems. Bioethics also features regular Background Briefings on important current debates in the field. These feature articles provide excellent material for bioethics scholars, teachers and students alike.
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