加州亚裔美国人、夏威夷原住民和太平洋岛民极低出生体重婴儿的支气管肺发育不良。

IF 3.5 2区医学 Q1 PEDIATRICS

Journal of Pediatrics Pub Date : 2025-06-26 DOI:10.1016/j.jpeds.2025.114706

Kalen Hendra MD , Xin Cui PhD, MPH , Elliot Main MD , Henry C. Lee MD , Scarlett Lin Gomez PhD, MPH , Salma Shariff-Marco PhD, MPH , Erik A. Jensen MD, MSCE , Jochen Profit MD, MPH

{"title":"加州亚裔美国人、夏威夷原住民和太平洋岛民极低出生体重婴儿的支气管肺发育不良。","authors":"Kalen Hendra MD , Xin Cui PhD, MPH , Elliot Main MD , Henry C. Lee MD , Scarlett Lin Gomez PhD, MPH , Salma Shariff-Marco PhD, MPH , Erik A. Jensen MD, MSCE , Jochen Profit MD, MPH","doi":"10.1016/j.jpeds.2025.114706","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To characterize incidences of bronchopulmonary dysplasia (BPD) and oxygen use at discharge in infants with very low birth weight by Asian American, Native Hawaiian, and Pacific Islander (AANHPI) ethnicity.</div></div><div><h3>Study design</h3><div>We studied infants with very low birth weight born in California from 2012 to 2019. Infants of AANHPI mothers were studied in aggregate, were disaggregated by maternal ethnicity, and were compared with infants of Black, Hispanic, and non-Hispanic White (NHW) mothers. BPD was defined as the use of supplemental oxygen at 36 weeks postmenstrual age. Multivariable generalized estimating equation Poisson regression models adjusting for infant, maternal, and hospital-level factors compared outcomes across racial and ethnic groups using NHW as the reference.</div></div><div><h3>Results</h3><div>We studied 29 467 infants whose mothers self-identified as AANHPI (n = 5002), Black (n = 3711), Hispanic (n = 14 168), and NHW (n = 6586). In infants of AANHPI mothers, incidences of BPD and oxygen use at discharge were 24.9% (disaggregated range: 16.9%-30.5%) and 9.2% (disaggregated range: 5.8%-14.5%), respectively. Compared with infants of NHW mothers, infants of Asian Indian mothers had a significantly lower risk of BPD (adjusted relative risk [aRR] 0.71) and oxygen use at discharge (aRR 0.66), whereas infants of Chinese and Korean mothers had a significantly higher risk of BPD (aRR 1.28 and aRR 1.45, respectively) and oxygen use at discharge (aRR 1.46 and aRR 1.77, respectively).</div></div><div><h3>Conclusions</h3><div>AANHPI data disaggregation demonstrated variability in incidences of BPD and oxygen use at discharge, and variability in risk compared with infants of NHW mothers. Our study highlights disparities across this diverse group that is typically studied in aggregate.</div></div>","PeriodicalId":54774,"journal":{"name":"Journal of Pediatrics","volume":"286 ","pages":"Article 114706"},"PeriodicalIF":3.5000,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Bronchopulmonary Dysplasia in Asian American, Native Hawaiian, and Pacific Islander Infants with Very Low Birth Weight in California\",\"authors\":\"Kalen Hendra MD , Xin Cui PhD, MPH , Elliot Main MD , Henry C. Lee MD , Scarlett Lin Gomez PhD, MPH , Salma Shariff-Marco PhD, MPH , Erik A. Jensen MD, MSCE , Jochen Profit MD, MPH\",\"doi\":\"10.1016/j.jpeds.2025.114706\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>To characterize incidences of bronchopulmonary dysplasia (BPD) and oxygen use at discharge in infants with very low birth weight by Asian American, Native Hawaiian, and Pacific Islander (AANHPI) ethnicity.</div></div><div><h3>Study design</h3><div>We studied infants with very low birth weight born in California from 2012 to 2019. Infants of AANHPI mothers were studied in aggregate, were disaggregated by maternal ethnicity, and were compared with infants of Black, Hispanic, and non-Hispanic White (NHW) mothers. BPD was defined as the use of supplemental oxygen at 36 weeks postmenstrual age. Multivariable generalized estimating equation Poisson regression models adjusting for infant, maternal, and hospital-level factors compared outcomes across racial and ethnic groups using NHW as the reference.</div></div><div><h3>Results</h3><div>We studied 29 467 infants whose mothers self-identified as AANHPI (n = 5002), Black (n = 3711), Hispanic (n = 14 168), and NHW (n = 6586). In infants of AANHPI mothers, incidences of BPD and oxygen use at discharge were 24.9% (disaggregated range: 16.9%-30.5%) and 9.2% (disaggregated range: 5.8%-14.5%), respectively. Compared with infants of NHW mothers, infants of Asian Indian mothers had a significantly lower risk of BPD (adjusted relative risk [aRR] 0.71) and oxygen use at discharge (aRR 0.66), whereas infants of Chinese and Korean mothers had a significantly higher risk of BPD (aRR 1.28 and aRR 1.45, respectively) and oxygen use at discharge (aRR 1.46 and aRR 1.77, respectively).</div></div><div><h3>Conclusions</h3><div>AANHPI data disaggregation demonstrated variability in incidences of BPD and oxygen use at discharge, and variability in risk compared with infants of NHW mothers. Our study highlights disparities across this diverse group that is typically studied in aggregate.</div></div>\",\"PeriodicalId\":54774,\"journal\":{\"name\":\"Journal of Pediatrics\",\"volume\":\"286 \",\"pages\":\"Article 114706\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2025-06-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Pediatrics\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0022347625002471\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PEDIATRICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Pediatrics","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0022347625002471","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PEDIATRICS","Score":null,"Total":0}

引用次数: 0

摘要

目的：了解亚裔美国人、夏威夷原住民和太平洋岛民（AANHPI）极低出生体重（VLBW）婴儿的支气管肺发育不良（BPD）发生率和出院时的氧气使用情况。研究设计：我们研究了2012-2019年在加州出生的VLBW婴儿。对AANHPI母亲的婴儿进行总体研究，按母亲种族分类，并与黑人、西班牙裔和非西班牙裔白人（NHW）母亲的婴儿进行比较。BPD定义为经后36周时补充氧的使用。多变量广义估计方程泊松回归模型调整了婴儿、母亲和医院水平的因素，以NHW为参考，比较了不同种族和民族群体的结果。结果：我们研究了29,467名婴儿，其母亲自我认定为AANHPI (n=5,002)，黑人（n=3,711），西班牙裔（n=14,168）和NHW （n=6,586）。在AANHPI母亲的婴儿中，BPD和出院时氧气使用的发生率分别为24.9%（分类范围：16.9%-30.5%）和9.2%（分类范围：5.8%-14.5%）。与NHW母亲的婴儿相比，亚洲印度母亲的婴儿BPD的风险（调整相对风险[aRR] 0.71）和出院时的氧气使用（aRR 0.66）显著较低，而中国和韩国母亲的婴儿BPD的风险（aRR分别为1.28和1.45）和出院时的氧气使用（aRR分别为1.46和1.77）显著较高。结论：AANHPI数据分析表明，与NHW母亲的婴儿相比，BPD的发病率和出院时的氧气使用存在差异，风险也存在差异。我们的研究强调了这一多样化群体之间的差异，而这一群体通常是在总体上进行研究的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Bronchopulmonary Dysplasia in Asian American, Native Hawaiian, and Pacific Islander Infants with Very Low Birth Weight in California

Objective

To characterize incidences of bronchopulmonary dysplasia (BPD) and oxygen use at discharge in infants with very low birth weight by Asian American, Native Hawaiian, and Pacific Islander (AANHPI) ethnicity.

Study design

We studied infants with very low birth weight born in California from 2012 to 2019. Infants of AANHPI mothers were studied in aggregate, were disaggregated by maternal ethnicity, and were compared with infants of Black, Hispanic, and non-Hispanic White (NHW) mothers. BPD was defined as the use of supplemental oxygen at 36 weeks postmenstrual age. Multivariable generalized estimating equation Poisson regression models adjusting for infant, maternal, and hospital-level factors compared outcomes across racial and ethnic groups using NHW as the reference.

Results

We studied 29 467 infants whose mothers self-identified as AANHPI (n = 5002), Black (n = 3711), Hispanic (n = 14 168), and NHW (n = 6586). In infants of AANHPI mothers, incidences of BPD and oxygen use at discharge were 24.9% (disaggregated range: 16.9%-30.5%) and 9.2% (disaggregated range: 5.8%-14.5%), respectively. Compared with infants of NHW mothers, infants of Asian Indian mothers had a significantly lower risk of BPD (adjusted relative risk [aRR] 0.71) and oxygen use at discharge (aRR 0.66), whereas infants of Chinese and Korean mothers had a significantly higher risk of BPD (aRR 1.28 and aRR 1.45, respectively) and oxygen use at discharge (aRR 1.46 and aRR 1.77, respectively).

Conclusions

AANHPI data disaggregation demonstrated variability in incidences of BPD and oxygen use at discharge, and variability in risk compared with infants of NHW mothers. Our study highlights disparities across this diverse group that is typically studied in aggregate.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Pediatrics 医学-小儿科

CiteScore

6.00

自引率

2.00%

发文量

696

审稿时长

31 days

期刊介绍： The Journal of Pediatrics is an international peer-reviewed journal that advances pediatric research and serves as a practical guide for pediatricians who manage health and diagnose and treat disorders in infants, children, and adolescents. The Journal publishes original work based on standards of excellence and expert review. The Journal seeks to publish high quality original articles that are immediately applicable to practice (basic science, translational research, evidence-based medicine), brief clinical and laboratory case reports, medical progress, expert commentary, grand rounds, insightful editorials, “classic” physical examinations, and novel insights into clinical and academic pediatric medicine related to every aspect of child health. Published monthly since 1932, The Journal of Pediatrics continues to promote the latest developments in pediatric medicine, child health, policy, and advocacy. Topics covered in The Journal of Pediatrics include, but are not limited to: General Pediatrics Pediatric Subspecialties Adolescent Medicine Allergy and Immunology Cardiology Critical Care Medicine Developmental-Behavioral Medicine Endocrinology Gastroenterology Hematology-Oncology Infectious Diseases Neonatal-Perinatal Medicine Nephrology Neurology Emergency Medicine Pulmonology Rheumatology Genetics Ethics Health Service Research Pediatric Hospitalist Medicine.