1型高草酸尿患者的慢性腿部溃疡：罕见且具有挑战性的诊断。

IF 0.4 Q3 MEDICINE, GENERAL & INTERNAL

Oxford Medical Case Reports Pub Date : 2025-06-27 eCollection Date: 2025-06-01 DOI:10.1093/omcr/omaf068

Soukayna Kabbou, Ouiam Eljouari, Salim Gallouj

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引用次数: 0

摘要

钙化反应是一种罕见但非常严重的疾病，其特征是全身内侧小动脉钙化，导致缺血和随后的组织坏死。我们报告一例29岁的女性，患有原发性高草酸尿1型和终末期肾脏疾病，在她的腿上出现了多处疼痛的溃疡，最初认为是由于皮肤草酸中毒。然而，病理结果显示钙化反应。钙化反应和高草酸尿的关联是罕见的，使本病例独特。给予内科治疗、高流量氧疗和先进的创面敷料以促进肉芽组织形成和优化溃疡愈合，并每日使用低钙透析液血液透析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Chronic leg ulcers in a patient with Hyperoxaluria type 1: a rare and challenging diagnosis.

Calciphylaxis is an uncommon yet highly severe condition characterized by systemic medial calcification of arterioles, leading to ischemia and subsequent tissue necrosis. we report the case of a 29 year-old female suffering from primary hyperoxaluria type 1 and end-stage renal disease, Developed multiple painful ulcerations on her legs, initially believed to be due to cutaneous oxalosis. However, pathology findings revealed calciphylaxis. The association calciphylaxis and hyperoxaluria is rare, making this case unique. and she was treated with medical therapy, high-flow oxygen therapy and advanced wound dressings to facilitate granulation tissue formation and optimize ulcer healing, and daily hemodialysis with a low-calcium dialysate.

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来源期刊

Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

125

审稿时长

19 weeks

期刊介绍： Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.