{"title":"使用e-规范法确定颈椎矢状位测量的参考值。","authors":"Shenyan Gu , Kaiwen Chen , Dongqing Zhu , Feizhou Lyu , Jianyuan Jiang , Joe F. Jabre , Xinlei Xia , Chaojun Zheng","doi":"10.1016/j.wneu.2025.124227","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the feasibility of the extrapolated norms (e-norms) method for establishing a reference range for the measurements of cervical sagittal alignment and to explore the differences in these ranges according to sex and age.</div></div><div><h3>Methods</h3><div>We applied the e-norms method to calculate reference values for the angle between occipital and C2 vertebrae, C2-7 Cobb angle, C2-7 sagittal vertical axis, and C7 slope in 1720 subjects. The e-norms values of these measurements were measured in different age subgroups of male or female subjects.</div></div><div><h3>Results</h3><div>According to the data points within the plateau obtained via e-norms method, normal angle between occipital and C2 vertebrae was 18.5<!--> <!-->± 2.6°, C2-7 Cobb angle was 8.8<!--> <!-->± 4.5°, C2-7 sagittal vertical axis was 1.5<!--> <!-->± 0.4 cm, and C7 slope was 20.1<!--> <!-->± 3.5°. These data points involved a total of 1617 (1617/1720, 94.0%) subjects, with only 191 (11.1%, 191/1720) subjects having all the cervical sagittal measurements included in the plateau. Both C2-7 Cobb angle and C7 slope e-norms values increase with age in females, whereas only C7 slope e-norms values increase with age in males. The males showed greater e-norms values in at least one of cervical sagittal measurements compared with females in different age subgroups (<em>P</em> < 0.05).</div></div><div><h3>Conclusions</h3><div>This study demonstrated that e-norms may be a simple, reliable and cost-saving approach for establishing reference values for cervical sagittal measurements. This new method allows us to establish reference values for sex or age subgroups to study the sex differences and trends with age of cervical sagittal alignment.</div></div>","PeriodicalId":23906,"journal":{"name":"World neurosurgery","volume":"200 ","pages":"Article 124227"},"PeriodicalIF":2.1000,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Determining the Reference Values of the Measurements of Cervical Sagittal Alignment Using the Extrapolated Norms Method\",\"authors\":\"Shenyan Gu , Kaiwen Chen , Dongqing Zhu , Feizhou Lyu , Jianyuan Jiang , Joe F. Jabre , Xinlei Xia , Chaojun Zheng\",\"doi\":\"10.1016/j.wneu.2025.124227\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><div>To investigate the feasibility of the extrapolated norms (e-norms) method for establishing a reference range for the measurements of cervical sagittal alignment and to explore the differences in these ranges according to sex and age.</div></div><div><h3>Methods</h3><div>We applied the e-norms method to calculate reference values for the angle between occipital and C2 vertebrae, C2-7 Cobb angle, C2-7 sagittal vertical axis, and C7 slope in 1720 subjects. The e-norms values of these measurements were measured in different age subgroups of male or female subjects.</div></div><div><h3>Results</h3><div>According to the data points within the plateau obtained via e-norms method, normal angle between occipital and C2 vertebrae was 18.5<!--> <!-->± 2.6°, C2-7 Cobb angle was 8.8<!--> <!-->± 4.5°, C2-7 sagittal vertical axis was 1.5<!--> <!-->± 0.4 cm, and C7 slope was 20.1<!--> <!-->± 3.5°. These data points involved a total of 1617 (1617/1720, 94.0%) subjects, with only 191 (11.1%, 191/1720) subjects having all the cervical sagittal measurements included in the plateau. Both C2-7 Cobb angle and C7 slope e-norms values increase with age in females, whereas only C7 slope e-norms values increase with age in males. The males showed greater e-norms values in at least one of cervical sagittal measurements compared with females in different age subgroups (<em>P</em> < 0.05).</div></div><div><h3>Conclusions</h3><div>This study demonstrated that e-norms may be a simple, reliable and cost-saving approach for establishing reference values for cervical sagittal measurements. This new method allows us to establish reference values for sex or age subgroups to study the sex differences and trends with age of cervical sagittal alignment.</div></div>\",\"PeriodicalId\":23906,\"journal\":{\"name\":\"World neurosurgery\",\"volume\":\"200 \",\"pages\":\"Article 124227\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2025-06-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World neurosurgery\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1878875025005832\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World neurosurgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1878875025005832","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
Determining the Reference Values of the Measurements of Cervical Sagittal Alignment Using the Extrapolated Norms Method
Objective
To investigate the feasibility of the extrapolated norms (e-norms) method for establishing a reference range for the measurements of cervical sagittal alignment and to explore the differences in these ranges according to sex and age.
Methods
We applied the e-norms method to calculate reference values for the angle between occipital and C2 vertebrae, C2-7 Cobb angle, C2-7 sagittal vertical axis, and C7 slope in 1720 subjects. The e-norms values of these measurements were measured in different age subgroups of male or female subjects.
Results
According to the data points within the plateau obtained via e-norms method, normal angle between occipital and C2 vertebrae was 18.5 ± 2.6°, C2-7 Cobb angle was 8.8 ± 4.5°, C2-7 sagittal vertical axis was 1.5 ± 0.4 cm, and C7 slope was 20.1 ± 3.5°. These data points involved a total of 1617 (1617/1720, 94.0%) subjects, with only 191 (11.1%, 191/1720) subjects having all the cervical sagittal measurements included in the plateau. Both C2-7 Cobb angle and C7 slope e-norms values increase with age in females, whereas only C7 slope e-norms values increase with age in males. The males showed greater e-norms values in at least one of cervical sagittal measurements compared with females in different age subgroups (P < 0.05).
Conclusions
This study demonstrated that e-norms may be a simple, reliable and cost-saving approach for establishing reference values for cervical sagittal measurements. This new method allows us to establish reference values for sex or age subgroups to study the sex differences and trends with age of cervical sagittal alignment.
期刊介绍:
World Neurosurgery has an open access mirror journal World Neurosurgery: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review.
The journal''s mission is to:
-To provide a first-class international forum and a 2-way conduit for dialogue that is relevant to neurosurgeons and providers who care for neurosurgery patients. The categories of the exchanged information include clinical and basic science, as well as global information that provide social, political, educational, economic, cultural or societal insights and knowledge that are of significance and relevance to worldwide neurosurgery patient care.
-To act as a primary intellectual catalyst for the stimulation of creativity, the creation of new knowledge, and the enhancement of quality neurosurgical care worldwide.
-To provide a forum for communication that enriches the lives of all neurosurgeons and their colleagues; and, in so doing, enriches the lives of their patients.
Topics to be addressed in World Neurosurgery include: EDUCATION, ECONOMICS, RESEARCH, POLITICS, HISTORY, CULTURE, CLINICAL SCIENCE, LABORATORY SCIENCE, TECHNOLOGY, OPERATIVE TECHNIQUES, CLINICAL IMAGES, VIDEOS