有色皮肤Decalvans毛囊炎的流行病学、临床和治疗见解:17例回顾性描述性研究。

IF 1.3 Q3 DERMATOLOGY
Zineb Loubaris, Hajar Elhassani Taib, Laila Benzekri, Mariame Meziane
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引用次数: 0

摘要

前言:脱斑疹性毛囊炎(FD)是一种中性粒细胞瘢痕性脱发,其特征是毛囊脓疱、结痂和毛发丛生。其病因尚不清楚,但金黄色葡萄球菌感染和免疫功能障碍有牵连。本研究在有色人种皮肤中调查FD的临床、皮肤镜和治疗方面。本研究的目的是分析FD患者的流行病学概况、临床多样性、诊断特征和治疗策略。方法:对拉巴特伊本西纳大学医院17例FD患者进行回顾性描述性研究,历时4年。诊断基于临床,皮肤镜和组织学检查结果。收集的数据包括人口统计学、疾病发病、合并症、症状、严重程度分级和治疗反应。结果:该队列包括17例患者(8男9女),中位年龄37.2岁。光型IV型居多(47.1%)。最主要的发病部位为顶点(82.4%)。所有病例均出现瘢痕性脱发,最常见的皮肤镜表现为毛囊周围红斑(100%)和毛发丛生(88.2%)。55.5%的女性患者严重程度为3级。局部和口服抗生素,包括强力霉素,是最常用的治疗方法。对治疗的抵抗在女性中更为常见。结论:有色皮肤患者的FD表现出与全球数据相当的临床、皮肤镜和治疗模式,尽管注意到更高的严重程度和脓疱患病率。强力霉素和局部药物仍然是主要的治疗选择。需要更大规模的研究来阐明发病机制和优化治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiological, Clinical, and Therapeutic Insights into Folliculitis Decalvans in Skin of Color: A Retrospective Descriptive Study of 17 Cases.

Introduction: Folliculitis decalvans (FD) is a neutrophilic scarring alopecia characterized by follicular pustules, crusts, and tufted hair. Its etiology remains unclear, though Staphylococcus aureus infection and immune dysfunction are implicated. This study investigates the clinical, dermoscopic, and therapeutic aspects of FD in a skin of color population. The objective of our study was to analyze the epidemiological profile, clinical diversity, diagnostic features, and treatment strategies for FD patients.

Methods: A retrospective, descriptive study of 17 FD patients was conducted at Ibn Sina University Hospital, Rabat, over 4 years. Diagnosis was based on clinical, dermoscopic, and histological findings. Data collected included demographics, disease onset, comorbidities, symptoms, severity grading, and therapeutic responses.

Results: The cohort comprised 17 patients (8 men, 9 women) with a median age of 37.2 years. Phototype IV was predominant (47.1%). The vertex was the most affected site (82.4%). Scarring alopecia was present in all cases, with perifollicular erythema (100%) and tufted hair (88.2%) being the most common dermoscopic findings. Grade 3 severity was observed in 55.5% of female patients. Topical and oral antibiotics, including doxycycline, were the most prescribed treatments. Resistance to treatment was more common in women.

Conclusions: FD in skin of color patients exhibits clinical, dermoscopic, and therapeutic patterns comparable to global data, though higher severity and pustule prevalence were noted. Doxycycline and topical agents remain key therapeutic options. Larger studies are needed to elucidate pathogenesis and optimize management strategies.

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CiteScore
2.00
自引率
10.00%
发文量
69
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