Michail E Keramidas, Heather M Bowes, Maaike I Moes, Ola Eiken, Mikael Gennser
{"title":"常压高氧对常温和轻度低温个体局部冷时手指血管舒缩和热感觉反应的影响。","authors":"Michail E Keramidas, Heather M Bowes, Maaike I Moes, Ola Eiken, Mikael Gennser","doi":"10.1007/s00421-025-05869-0","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>To evaluate whether a sustained period of normobaric O<sub>2</sub> breathing would modulate acral-skin vasoreactivity and thermosensitivity to localised cooling.</p><p><strong>Methods: </strong>Eight healthy men performed a 30-min normoxic and hyperoxic (100% O<sub>2</sub>) hand cold (8 °C water) provocation, while immersed to the chest either in 35.1 (0.4)°C (normothermic trial) or in 21.0 (0.1)°C (hypothermic trial) water. Finger temperature, circulatory and perceptual responses were monitored.</p><p><strong>Results: </strong>During the normothermic trial, hyperoxia augmented the cold-induced drop in finger temperature, and attenuated the rewarming (P = 0.03). Hyperoxia also enhanced the sensation of pain (P = 0.04). During the hypothermic trial, hyperoxia did not modify finger temperature, circulatory and perceptual responses to cold (P > 0.05).</p><p><strong>Conclusion: </strong>In normothermia, hyperoxia aggravates finger cold-induced vasoconstriction and pain sensation. In mild hypothermia, however, any hyperoxia-evoked influence on finger vasomotion and thermonociception is overridden by the generalised vasoconstriction and thermal discomfort instigated by whole-body cooling.</p>","PeriodicalId":12005,"journal":{"name":"European Journal of Applied Physiology","volume":" ","pages":""},"PeriodicalIF":2.8000,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of normobaric hyperoxia on finger vasomotor and thermoperceptual responses to local cold in normothermic and mildly hypothermic individuals.\",\"authors\":\"Michail E Keramidas, Heather M Bowes, Maaike I Moes, Ola Eiken, Mikael Gennser\",\"doi\":\"10.1007/s00421-025-05869-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>To evaluate whether a sustained period of normobaric O<sub>2</sub> breathing would modulate acral-skin vasoreactivity and thermosensitivity to localised cooling.</p><p><strong>Methods: </strong>Eight healthy men performed a 30-min normoxic and hyperoxic (100% O<sub>2</sub>) hand cold (8 °C water) provocation, while immersed to the chest either in 35.1 (0.4)°C (normothermic trial) or in 21.0 (0.1)°C (hypothermic trial) water. Finger temperature, circulatory and perceptual responses were monitored.</p><p><strong>Results: </strong>During the normothermic trial, hyperoxia augmented the cold-induced drop in finger temperature, and attenuated the rewarming (P = 0.03). Hyperoxia also enhanced the sensation of pain (P = 0.04). During the hypothermic trial, hyperoxia did not modify finger temperature, circulatory and perceptual responses to cold (P > 0.05).</p><p><strong>Conclusion: </strong>In normothermia, hyperoxia aggravates finger cold-induced vasoconstriction and pain sensation. In mild hypothermia, however, any hyperoxia-evoked influence on finger vasomotion and thermonociception is overridden by the generalised vasoconstriction and thermal discomfort instigated by whole-body cooling.</p>\",\"PeriodicalId\":12005,\"journal\":{\"name\":\"European Journal of Applied Physiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.8000,\"publicationDate\":\"2025-06-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Applied Physiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00421-025-05869-0\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PHYSIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Applied Physiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00421-025-05869-0","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PHYSIOLOGY","Score":null,"Total":0}
Impact of normobaric hyperoxia on finger vasomotor and thermoperceptual responses to local cold in normothermic and mildly hypothermic individuals.
Aim: To evaluate whether a sustained period of normobaric O2 breathing would modulate acral-skin vasoreactivity and thermosensitivity to localised cooling.
Methods: Eight healthy men performed a 30-min normoxic and hyperoxic (100% O2) hand cold (8 °C water) provocation, while immersed to the chest either in 35.1 (0.4)°C (normothermic trial) or in 21.0 (0.1)°C (hypothermic trial) water. Finger temperature, circulatory and perceptual responses were monitored.
Results: During the normothermic trial, hyperoxia augmented the cold-induced drop in finger temperature, and attenuated the rewarming (P = 0.03). Hyperoxia also enhanced the sensation of pain (P = 0.04). During the hypothermic trial, hyperoxia did not modify finger temperature, circulatory and perceptual responses to cold (P > 0.05).
Conclusion: In normothermia, hyperoxia aggravates finger cold-induced vasoconstriction and pain sensation. In mild hypothermia, however, any hyperoxia-evoked influence on finger vasomotion and thermonociception is overridden by the generalised vasoconstriction and thermal discomfort instigated by whole-body cooling.
期刊介绍：
The European Journal of Applied Physiology (EJAP) aims to promote mechanistic advances in human integrative and translational physiology. Physiology is viewed broadly, having overlapping context with related disciplines such as biomechanics, biochemistry, endocrinology, ergonomics, immunology, motor control, and nutrition. EJAP welcomes studies dealing with physical exercise, training and performance. Studies addressing physiological mechanisms are preferred over descriptive studies. Papers dealing with animal models or pathophysiological conditions are not excluded from consideration, but must be clearly relevant to human physiology.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
