走向自然肢体功能:假肢创新的新时代。

IF 8.1 1区 医学 Q1 CLINICAL NEUROLOGY
Yucheng Tian, Dylan M Wallace, Paul S Cederna, Cynthia A Chestek, Stephen W P Kemp
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引用次数: 0

摘要

在过去的十年中,神经义肢的临床应用取得了突破性进展,它由来自周围目标(如神经和肌肉)和大脑的信号驱动,用于恢复肢体丧失或损伤的个体的肢体功能。在这篇综述中,我们重点介绍了最近在周围神经假肢直接与神经、残余肌肉和再神经支配肌肉接口方面的关键临床试验。然后,我们强调了脑接口的关键进展,包括使用脑电图、皮质电图和皮质内电极来控制神经假肢的临床试验。最后,我们探索神经义肢控制的未来,其中外周和脑接口可以结合起来提高神经义肢的性能。Ann neurol 2025。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Toward Natural Limb Function: A New Era in Prosthetic Innovation.

The past decade has witnessed groundbreaking clinical implementation of neuroprosthetic limbs driven by signals from peripheral targets (eg, nerves and muscle) and the brain to restore limb function for individuals with limb loss or impairment. In this review, we highlight recent key clinical trials in peripheral neuroprosthetic interfaces directly with nerve, residual muscle, and reinnervated muscle. We then highlight the key advances in brain interfaces, including clinical trials using electroencephalography, electrocorticography, and intracortical electrodes to control neuroprosthetics. Finally, we explore the future of neuroprosthetic control where both peripheral and brain interfaces can be combined to improve neuroprosthetic performance. ANN NEUROL 2025.

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来源期刊
Annals of Neurology
Annals of Neurology 医学-临床神经学
CiteScore
18.00
自引率
1.80%
发文量
270
审稿时长
3-8 weeks
期刊介绍: Annals of Neurology publishes original articles with potential for high impact in understanding the pathogenesis, clinical and laboratory features, diagnosis, treatment, outcomes and science underlying diseases of the human nervous system. Articles should ideally be of broad interest to the academic neurological community rather than solely to subspecialists in a particular field. Studies involving experimental model system, including those in cell and organ cultures and animals, of direct translational relevance to the understanding of neurological disease are also encouraged.
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