{"title":"肾移植受者迟发性难治性麦氏分枝杆菌腹壁脓肿1例","authors":"Hisashi Sakurai, Teppei Okamoto, Tomoko Hamaya, Hirotake Kodama, Naoki Fujita, Hayato Yamamoto, Kazuyuki Mori, Takeshi Fujita, Atushi Imai, Reiichi Murakami, Hirofumi Tomita, Shingo Hatakeyama","doi":"10.1002/iju5.70042","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Introduction</h3>\n \n <p><i>Mycobacterium mageritense</i> (<i>M. mageritense</i>), a rare non-tuberculous mycobacterium (NTM), can cause infections in immunocompromised patients, including kidney transplant recipients. We present a case of an abdominal wall abscess caused by <i>M. mageritense</i> following a living donor kidney transplant.</p>\n </section>\n \n <section>\n \n <h3> Case Presentation</h3>\n \n <p>A 58-year-old woman, post-ABO-incompatible kidney transplant, developed an abscess at the site of a removed peritoneal dialysis catheter. Initial antibiotics were ineffective, and pus cultures identified <i>M. mageritense</i>. Surgical drainage and levofloxacin-linezolid therapy controlled the infection temporarily. Despite clinical improvement, the abscess recurred 30 days post-discharge, which required repeated antibiotic use and adjustments to immunosuppression. Reducing mycophenolate mofetil while maintaining tacrolimus stabilized the infection, and prophylactic levofloxacin was continued post-discharge to prevent relapse.</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Effective infection control requires careful immunosuppressive adjustment and long-term antibiotic use to balance graft preservation with infection risk.</p>\n </section>\n </div>","PeriodicalId":52909,"journal":{"name":"IJU Case Reports","volume":"8 4","pages":"369-372"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70042","citationCount":"0","resultStr":"{\"title\":\"A Case of Delayed Refractory Mycobacterium mageritense Abdominal Wall Abscess in a Kidney Transplant Recipient\",\"authors\":\"Hisashi Sakurai, Teppei Okamoto, Tomoko Hamaya, Hirotake Kodama, Naoki Fujita, Hayato Yamamoto, Kazuyuki Mori, Takeshi Fujita, Atushi Imai, Reiichi Murakami, Hirofumi Tomita, Shingo Hatakeyama\",\"doi\":\"10.1002/iju5.70042\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Introduction</h3>\\n \\n <p><i>Mycobacterium mageritense</i> (<i>M. mageritense</i>), a rare non-tuberculous mycobacterium (NTM), can cause infections in immunocompromised patients, including kidney transplant recipients. We present a case of an abdominal wall abscess caused by <i>M. mageritense</i> following a living donor kidney transplant.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Case Presentation</h3>\\n \\n <p>A 58-year-old woman, post-ABO-incompatible kidney transplant, developed an abscess at the site of a removed peritoneal dialysis catheter. Initial antibiotics were ineffective, and pus cultures identified <i>M. mageritense</i>. Surgical drainage and levofloxacin-linezolid therapy controlled the infection temporarily. Despite clinical improvement, the abscess recurred 30 days post-discharge, which required repeated antibiotic use and adjustments to immunosuppression. Reducing mycophenolate mofetil while maintaining tacrolimus stabilized the infection, and prophylactic levofloxacin was continued post-discharge to prevent relapse.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Effective infection control requires careful immunosuppressive adjustment and long-term antibiotic use to balance graft preservation with infection risk.</p>\\n </section>\\n </div>\",\"PeriodicalId\":52909,\"journal\":{\"name\":\"IJU Case Reports\",\"volume\":\"8 4\",\"pages\":\"369-372\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/iju5.70042\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IJU Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/iju5.70042\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IJU Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/iju5.70042","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
A Case of Delayed Refractory Mycobacterium mageritense Abdominal Wall Abscess in a Kidney Transplant Recipient
Introduction
Mycobacterium mageritense (M. mageritense), a rare non-tuberculous mycobacterium (NTM), can cause infections in immunocompromised patients, including kidney transplant recipients. We present a case of an abdominal wall abscess caused by M. mageritense following a living donor kidney transplant.
Case Presentation
A 58-year-old woman, post-ABO-incompatible kidney transplant, developed an abscess at the site of a removed peritoneal dialysis catheter. Initial antibiotics were ineffective, and pus cultures identified M. mageritense. Surgical drainage and levofloxacin-linezolid therapy controlled the infection temporarily. Despite clinical improvement, the abscess recurred 30 days post-discharge, which required repeated antibiotic use and adjustments to immunosuppression. Reducing mycophenolate mofetil while maintaining tacrolimus stabilized the infection, and prophylactic levofloxacin was continued post-discharge to prevent relapse.
Conclusion
Effective infection control requires careful immunosuppressive adjustment and long-term antibiotic use to balance graft preservation with infection risk.