肾移植受者迟发性难治性麦氏分枝杆菌腹壁脓肿1例

Q4 Medicine
Hisashi Sakurai, Teppei Okamoto, Tomoko Hamaya, Hirotake Kodama, Naoki Fujita, Hayato Yamamoto, Kazuyuki Mori, Takeshi Fujita, Atushi Imai, Reiichi Murakami, Hirofumi Tomita, Shingo Hatakeyama
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引用次数: 0

摘要

mageritense分枝杆菌(M. mageritense)是一种罕见的非结核分枝杆菌(NTM),可引起免疫功能低下患者感染,包括肾移植受者。我们提出一个病例腹壁脓肿引起的马格利氏分枝杆菌继活体供体肾移植。病例介绍一名58岁女性,abo血型不相容肾移植后,在取出腹膜透析导管的部位出现脓肿。最初的抗生素无效,脓液培养鉴定出马氏分枝杆菌。手术引流和左氧氟沙星-利奈唑胺治疗暂时控制了感染。尽管临床好转,出院后30天脓肿复发,需要反复使用抗生素和调整免疫抑制。在维持他克莫司的同时减少霉酚酸酯可稳定感染,出院后继续预防性左氧氟沙星预防复发。结论有效的感染控制需要谨慎的免疫抑制调节和长期使用抗生素来平衡移植物保存和感染风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

A Case of Delayed Refractory Mycobacterium mageritense Abdominal Wall Abscess in a Kidney Transplant Recipient

A Case of Delayed Refractory Mycobacterium mageritense Abdominal Wall Abscess in a Kidney Transplant Recipient

Introduction

Mycobacterium mageritense (M. mageritense), a rare non-tuberculous mycobacterium (NTM), can cause infections in immunocompromised patients, including kidney transplant recipients. We present a case of an abdominal wall abscess caused by M. mageritense following a living donor kidney transplant.

Case Presentation

A 58-year-old woman, post-ABO-incompatible kidney transplant, developed an abscess at the site of a removed peritoneal dialysis catheter. Initial antibiotics were ineffective, and pus cultures identified M. mageritense. Surgical drainage and levofloxacin-linezolid therapy controlled the infection temporarily. Despite clinical improvement, the abscess recurred 30 days post-discharge, which required repeated antibiotic use and adjustments to immunosuppression. Reducing mycophenolate mofetil while maintaining tacrolimus stabilized the infection, and prophylactic levofloxacin was continued post-discharge to prevent relapse.

Conclusion

Effective infection control requires careful immunosuppressive adjustment and long-term antibiotic use to balance graft preservation with infection risk.

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来源期刊
IJU Case Reports
IJU Case Reports Medicine-Urology
CiteScore
0.60
自引率
0.00%
发文量
147
审稿时长
15 weeks
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