同时测定大戟、大戟和狼毒根中9种化合物的抗肿瘤活性

IF 1.3 3区医学 Q3 CHEMISTRY, APPLIED

Journal of Asian Natural Products Research Pub Date : 2025-07-03 DOI:10.1080/10286020.2024.2442444

Lin-Mei Zhang , Yu Yan , Fan Zhang , Kang Ding , Jia Zhang , Hua Yang , Wei-Ku Zhang , Jun He , Jie-Kun Xu

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引用次数: 0

摘要

Langdu通常被认为是Euphorbia fischeriana， Euphorbia ebracteolata和Stellera chamaejasme的根。然而，这三种植物能否相互替代一直是人们关注的问题。本文旨在阐明三种朗渡属植物在化学成分和抗肿瘤作用方面的差异。本研究对朗度样品中8种二萜和1种黄酮类化合物进行了定性和定量分析，并绘制了IC50曲线，为鉴定和使用提供依据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Simultaneous determination of nine compounds from the roots of Euphorbia fischeriana, Euphorbia ebracteolata and Stellera chamaejasme and their anti-tumor activities

Langdu is generally considered as the roots of Euphorbia fischeriana, Euphorbia ebracteolata and Stellera chamaejasme. However, whether these three plants can substitute for one another has always been a concern. This article aims to clarify the differences among the three Langdu species in chemical constituents and anti-tumor effects. This study provides a qualitative and quantitative analysis of eight diterpenoids and one flavonoid in Langdu samples and IC₅₀ curves for these compounds, which can serve as a basis for identification and usage.

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来源期刊

Journal of Asian Natural Products Research 医学-药学

CiteScore

3.20

自引率

5.90%

发文量

审稿时长

2.3 months

期刊介绍： The Journal of Asian Natural Products Research (JANPR) publishes chemical and pharmaceutical studies in the English language in the field of natural product research on Asian ethnic medicine. The journal publishes work from scientists in Asian countries, e.g. China, Japan, Korea and India, including contributions from other countries concerning natural products of Asia. The journal is chemistry-orientated. Major fields covered are: isolation and structural elucidation of natural constituents (including those for non-medical uses), synthesis and transformation (including biosynthesis and biotransformation) of natural products, pharmacognosy, and allied topics. Biological evaluation of crude extracts are acceptable only as supporting data for pure isolates with well-characterized structures. All published research articles in this journal have undergone rigorous peer review, based on initial editor screening and anonymized refereeing by at least two expert referees.