肌肉需要NAD，但需要多少呢？

IF 30.9 1区生物学 Q1 CELL BIOLOGY

Cell metabolism Pub Date : 2025-07-01 DOI:10.1016/j.cmet.2025.06.001

David W. Frederick, Joseph P. McGaunn, Joseph A. Baur

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引用次数: 0

摘要

增加烟酰胺腺嘌呤二核苷酸（NAD）的补充剂越来越受欢迎，许多注意力都集中在对骨骼肌的潜在益处上。在这一期的《细胞代谢》中，Chubanava等人使用诱导模型降低了成年小鼠肌肉中的NAD浓度，揭示了令人惊讶的缺乏功能后果。

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Muscle needs NAD, but how much?

Supplements that increase nicotinamide adenine dinucleotide (NAD) have become increasingly popular, and much of the attention has focused on potential benefits to skeletal muscle. In this issue of Cell Metabolism, Chubanava et al.¹ use an inducible model to lower NAD concentration in the muscles of adult mice, revealing a surprising lack of functional consequences.

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来源期刊

Cell metabolism 生物-内分泌学与代谢

CiteScore

48.60

自引率

1.40%

发文量

173

审稿时长

2.5 months

期刊介绍： Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.