Manahil Mubeen, Aasiya Shahbaz Sakarwala, Arif Imdad Bijarani, Muhammad Taha Kamal
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Enhancing Heart Health: Expanding the Use of SGLT2 Inhibitors in Cardiovascular Disease
SGLT2 inhibitors offer multifaceted cardiovascular benefits, including improved cardiac metabolism, reduced preload and afterload, and decreased myocardial infarction risk. These effects are driven by renoprotection, anti-inflammatory properties, improved mitochondrial function, osmotic diuresis, and glycemic control. Together, these mechanisms support the role of SGLT2 inhibitors in reducing cardiovascular morbidity and mortality.
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