{"title":"用Hounsfield单位值评价强直性脊柱炎患者的椎骨","authors":"Junya Hasegawa, Mochihito Suzuki, Kenji Kishimoto, Ryo Sato, Yusuke Ohno, Takaya Sugiura, Hiroto Yamamoto, Kenya Terabe, Shuji Asai, Shiro Imagama","doi":"10.1111/1756-185X.70332","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>To evaluate vertebral Hounsfield Unit (HU) values on computed tomography (CT) in patients with ankylosing spondylitis (AS) compared to patients without AS and to examine differences in HU values between ankylosed and nonankylosed vertebrae in patients with AS.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>This cross-sectional study included 34 patients with AS and 73 patients without AS who underwent spinal CT between 2004 and 2022. HU values were measured from C3 to L5 in patients with AS and from L1 to L5 in patients without AS. Propensity score (PS) matching based on age and sex was performed to compare HU values between groups. Additionally, HU values were compared between ankylosed and nonankylosed vertebrae within the AS group.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>After PS matching, vertebral HU values were significantly lower in patients with AS than in patients without AS (136.4 vs. 197.1, <i>p</i> = 0.009). Among patients with AS, HU values were highest in the cervical spine, followed by the thoracic and lumbar regions. Ankylosed vertebrae showed significantly lower HU values than nonankylosed vertebrae across all spinal levels (<i>p</i> < 0.001).</p>\n </section>\n \n <section>\n \n <h3> Conclusion</h3>\n \n <p>Vertebral HU values were lower in patients with AS compared to age- and sex-matched patients without AS. HU values were highest in the cervical spine, and ankylosed vertebrae consistently exhibited lower HU values than nonankylosed vertebrae across all spinal regions.</p>\n </section>\n </div>","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 7","pages":""},"PeriodicalIF":2.0000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Evaluation of Vertebrae in Patients With Ankylosing Spondylitis Using Hounsfield Unit Values\",\"authors\":\"Junya Hasegawa, Mochihito Suzuki, Kenji Kishimoto, Ryo Sato, Yusuke Ohno, Takaya Sugiura, Hiroto Yamamoto, Kenya Terabe, Shuji Asai, Shiro Imagama\",\"doi\":\"10.1111/1756-185X.70332\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>To evaluate vertebral Hounsfield Unit (HU) values on computed tomography (CT) in patients with ankylosing spondylitis (AS) compared to patients without AS and to examine differences in HU values between ankylosed and nonankylosed vertebrae in patients with AS.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>This cross-sectional study included 34 patients with AS and 73 patients without AS who underwent spinal CT between 2004 and 2022. HU values were measured from C3 to L5 in patients with AS and from L1 to L5 in patients without AS. Propensity score (PS) matching based on age and sex was performed to compare HU values between groups. Additionally, HU values were compared between ankylosed and nonankylosed vertebrae within the AS group.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>After PS matching, vertebral HU values were significantly lower in patients with AS than in patients without AS (136.4 vs. 197.1, <i>p</i> = 0.009). Among patients with AS, HU values were highest in the cervical spine, followed by the thoracic and lumbar regions. Ankylosed vertebrae showed significantly lower HU values than nonankylosed vertebrae across all spinal levels (<i>p</i> < 0.001).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusion</h3>\\n \\n <p>Vertebral HU values were lower in patients with AS compared to age- and sex-matched patients without AS. 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引用次数: 0
摘要
目的评价强直性脊柱炎（AS）患者与非强直性脊柱炎患者椎体Hounsfield Unit （HU）的CT值，并探讨强直性脊柱炎（AS）患者与非强直性脊柱炎患者椎体HU值的差异。方法本横断面研究纳入2004年至2022年间行脊柱CT的34例AS患者和73例非AS患者。测量AS患者从C3到L5的HU值，非AS患者从L1到L5的HU值。采用基于年龄和性别的倾向评分（PS）匹配来比较各组间的HU值。此外，比较AS组内强直性椎体和非强直性椎体的HU值。结果经PS匹配后，AS患者椎体HU值明显低于非AS患者（136.4 vs. 197.1, p = 0.009）。在AS患者中，HU值在颈椎最高，其次是胸椎和腰椎。在所有脊柱水平上，强直性椎体的HU值明显低于非强直性椎体（p < 0.001）。结论与年龄和性别匹配的非AS患者相比，AS患者椎体HU值较低。HU值在颈椎中最高，并且在所有脊柱区域中，强直性椎体的HU值始终低于非强直性椎体。
Evaluation of Vertebrae in Patients With Ankylosing Spondylitis Using Hounsfield Unit Values
Objective
To evaluate vertebral Hounsfield Unit (HU) values on computed tomography (CT) in patients with ankylosing spondylitis (AS) compared to patients without AS and to examine differences in HU values between ankylosed and nonankylosed vertebrae in patients with AS.
Methods
This cross-sectional study included 34 patients with AS and 73 patients without AS who underwent spinal CT between 2004 and 2022. HU values were measured from C3 to L5 in patients with AS and from L1 to L5 in patients without AS. Propensity score (PS) matching based on age and sex was performed to compare HU values between groups. Additionally, HU values were compared between ankylosed and nonankylosed vertebrae within the AS group.
Results
After PS matching, vertebral HU values were significantly lower in patients with AS than in patients without AS (136.4 vs. 197.1, p = 0.009). Among patients with AS, HU values were highest in the cervical spine, followed by the thoracic and lumbar regions. Ankylosed vertebrae showed significantly lower HU values than nonankylosed vertebrae across all spinal levels (p < 0.001).
Conclusion
Vertebral HU values were lower in patients with AS compared to age- and sex-matched patients without AS. HU values were highest in the cervical spine, and ankylosed vertebrae consistently exhibited lower HU values than nonankylosed vertebrae across all spinal regions.
期刊介绍：
The International Journal of Rheumatic Diseases (formerly APLAR Journal of Rheumatology) is the official journal of the Asia Pacific League of Associations for Rheumatology. The Journal accepts original articles on clinical or experimental research pertinent to the rheumatic diseases, work on connective tissue diseases and other immune and allergic disorders. The acceptance criteria for all papers are the quality and originality of the research and its significance to our readership. Except where otherwise stated, manuscripts are peer reviewed by two anonymous reviewers and the Editor.
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