Liyuan Wang , Shwu-Jen Chang , Ching-Jung Chen , Jen-Tsai Liu
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Metal-organic frameworks for electrochemical glucose sensors: progress and challenges
The development of efficient, reliable, and sensitive glucose sensors is crucial for advancing medical diagnostics and health monitoring. Metal-organic frameworks (MOFs), characterized by high surface areas, tunable porosity, customizable functional sites, and catalytic properties, have emerged as promising materials for improving the performance of electrochemical glucose sensors. This review highlights recent progress in MOF-based platforms for both enzymatic and non-enzymatic glucose sensing. The mechanisms by which MOFs improve sensor performance in these systems are analyzed, focusing on their capabilities for enzyme immobilization, peroxidase-like activity, and catalysis in glucose oxidation. This review also examines the application of MOFs as immobilization matrices for enzymes and other electrochemical sensors. Additionally, the review addresses the challenges associated with MOF-based sensing technologies and explores potential solutions for their advancement.
期刊介绍:
Coordination Chemistry Reviews offers rapid publication of review articles on current and significant topics in coordination chemistry, encompassing organometallic, supramolecular, theoretical, and bioinorganic chemistry. It also covers catalysis, materials chemistry, and metal-organic frameworks from a coordination chemistry perspective. Reviews summarize recent developments or discuss specific techniques, welcoming contributions from both established and emerging researchers.
The journal releases special issues on timely subjects, including those featuring contributions from specific regions or conferences. Occasional full-length book articles are also featured. Additionally, special volumes cover annual reviews of main group chemistry, transition metal group chemistry, and organometallic chemistry. These comprehensive reviews are vital resources for those engaged in coordination chemistry, further establishing Coordination Chemistry Reviews as a hub for insightful surveys in inorganic and physical inorganic chemistry.