肝内科经颈静脉诊断程序：指征、技术和解释

IF 7.5 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

JHEP Reports Pub Date : 2025-04-29 DOI:10.1016/j.jhepr.2025.101437

Dominik Bettinger , Annalisa Berzigotti , Mattias Mandorfer , Cristina Ripoll , Christian Labenz , Eugen Zizer , Tony Bruns , Andrea De Gottardi , Johannes Emrich , Cornelius Engelmann , Benjamin Maasoumy , Arnulf Ferlitsch , Valentin Fuhrmann , Jan Hinrichs , Christian Jansen , Karoline Lackner , Robert Matzberger , Carsten Meyer , Behrang Mozayani , Michael Praktiknjo , Matthias M. Dollinger

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引用次数: 0

摘要

肝静脉压梯度测量（HVPG）和经颈静脉肝活检已成为临床肝病学的重要工具。HVPG的测量被认为是检测具有临床意义的门脉高压的金标准，HVPG≥10 mmHg是代偿性晚期慢性肝病(cACLD；补偿肝硬化)。经静脉肝活检可以在相同的程序中进行，对于凝血功能障碍、腹水和/或明显肥胖的患者，经静脉肝活检可能优于经皮肝活检。内窥镜超声引导的手术目前正在研究中，需要标准化。本文总结了HVPG测量和经颈静脉肝活检的关键技术方面，并详细概述了它们在新兴的非侵入性检查和内窥镜检查方法中的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Transjugular diagnostic procedures in hepatology: Indications, techniques and interpretation

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Transjugular diagnostic procedures in hepatology: Indications, techniques and interpretation

Measurement of the hepatic venous pressure gradient (HVPG) and transjugular liver biopsy have emerged as important tools in clinical hepatology. Measurement of HVPG is considered the gold standard for detecting clinically significant portal hypertension, with an HVPG of ≥10 mmHg being the key prognostic threshold in patients with compensated advanced chronic liver disease (cACLD; compensated cirrhosis). A transjugular liver biopsy can be obtained within the same procedure and may be preferred over percutaneous liver biopsy in patients with coagulopathy, ascites and/or significant obesity. Endoscopic ultrasound-guided procedures are currently under investigation and require standardisation. This article summarises critical technical aspects of HVPG measurements and transjugular liver biopsy and provides a detailed overview of their current role in the context of emerging non-invasive tests and endoscopic approaches.

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来源期刊

JHEP Reports GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

12.40

自引率

2.40%

发文量

161

审稿时长

36 days

期刊介绍： JHEP Reports is an open access journal that is affiliated with the European Association for the Study of the Liver (EASL). It serves as a companion journal to the highly respected Journal of Hepatology. The primary objective of JHEP Reports is to publish original papers and reviews that contribute to the advancement of knowledge in the field of liver diseases. The journal covers a wide range of topics, including basic, translational, and clinical research. It also focuses on global issues in hepatology, with particular emphasis on areas such as clinical trials, novel diagnostics, precision medicine and therapeutics, cancer research, cellular and molecular studies, artificial intelligence, microbiome research, epidemiology, and cutting-edge technologies. In summary, JHEP Reports is dedicated to promoting scientific discoveries and innovations in liver diseases through the publication of high-quality research papers and reviews covering various aspects of hepatology.