由巴氏芽孢菌引起的致死性肺真菌病在印度肾移植受者中的发生

IF 1.8 4区医学 Q3 MYCOLOGY

Journal de mycologie medicale Pub Date : 2025-06-20 DOI:10.1016/j.mycmed.2025.101561

Harsimran Kaur , Stephen Raj , Kapil Gothwal , Deepesh Kenwar , Valliappan Muthu , Haseen Ahmad , Parikshaa Gupta , Sourav Agnihotri , Ashish Sharma , Shivaprakash M Rudramurthy

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引用次数: 0

摘要

我们描述了一个罕见的病例肺部感染新兴的二态真菌，巴氏芽孢杆菌在一个73岁的肾移植受者从印度北部。病人出现发烧和呼吸急促的症状长达十天。支气管肺泡灌洗显示酵母细胞和巴氏杆菌生长，经内部转录间隔区（ITS）和rDNA大亚基测序证实。尽管用两性霉素B脂质体和伊曲康唑进行抗真菌治疗，他还是死于此病。该病例强调了巴氏杆菌在肾移植受者中的出现。

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Fatal pulmonary mycoses by Emergomyces pasteurianus in a renal transplant recipient from India

We describe a rare case of pulmonary infection by an emerging dimorphic fungus, Emergomyces pasteurianus in a 73-year-old renal transplant recipient from Northern India. The patient presented with fever and shortness of breath for ten days. The bronchoalveolar lavage revealed yeast cells and grew E. pasteurianus confirmed by sequencing internal transcribed spacer (ITS) region and large subunit of rDNA. He succumbed to the illness despite antifungal therapy comprising of liposomal amphotericin B followed by itraconazole. The case emphasizes the emergence of E. pasteurianus in renal transplant recipients.

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来源期刊

Journal de mycologie medicale 医学-真菌学

CiteScore

5.10

自引率

2.80%

发文量

审稿时长

6-12 weeks

期刊介绍： The Journal de Mycologie Medicale / Journal of Medical Mycology (JMM) publishes in English works dealing with human and animal mycology. The subjects treated are focused in particular on clinical, diagnostic, epidemiological, immunological, medical, pathological, preventive or therapeutic aspects of mycoses. Also covered are basic aspects linked primarily with morphology (electronic and photonic microscopy), physiology, biochemistry, cellular and molecular biology, immunochemistry, genetics, taxonomy or phylogeny of pathogenic or opportunistic fungi and actinomycetes in humans or animals. Studies of natural products showing inhibitory activity against pathogenic fungi cannot be considered without chemical characterization and identification of the compounds responsible for the inhibitory activity. JMM publishes (guest) editorials, original articles, reviews (and minireviews), case reports, technical notes, letters to the editor and information. Only clinical cases with real originality (new species, new clinical present action, new geographical localization, etc.), and fully documented (identification methods, results, etc.), will be considered. Under no circumstances does the journal guarantee publication before the editorial board makes its final decision. The journal is indexed in the main international databases and is accessible worldwide through the ScienceDirect and ClinicalKey platforms.