{"title":"设计了可编程胶体原子电子当量的自组装","authors":"Xiuyang Xia, Yuhan Peng, Ka Ki Li and Ran Ni","doi":"10.1088/1361-6633/ade625","DOIUrl":null,"url":null,"abstract":"To unlock the potential for assembling complex colloidal ‘molecules’, we investigate a minimal binary system of programmable colloidal atom-electron equivalents (PAE-EE), where electron equivalents (EEs) are multivalent linkers with two distinct types of single-stranded DNA (ssDNA) ends complementary to those ssDNAs on binary programmable atom equivalents (PAEs). We derive a statistical mechanical framework for calculating the effective interaction between PAEs mediated by EEs with arbitrary valency, which quantitatively agrees with simulations using explicit EEs. Our analysis reveals an anomalous dependence of PAE-PAE interactions on the EE valency, showing that EE-mediated interactions converge at the large valency limit. Moreover, we identify an optimal EE valency that maximizes the interaction difference between targeted and non-targeted binding pairs of PAEs. These findings offer design principles for targeted self-assembly in PAE-EE systems.","PeriodicalId":21110,"journal":{"name":"Reports on Progress in Physics","volume":"27 1","pages":""},"PeriodicalIF":19.0000,"publicationDate":"2025-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Designed self-assembly of programmable colloidal atom-electron equivalents\",\"authors\":\"Xiuyang Xia, Yuhan Peng, Ka Ki Li and Ran Ni\",\"doi\":\"10.1088/1361-6633/ade625\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"To unlock the potential for assembling complex colloidal ‘molecules’, we investigate a minimal binary system of programmable colloidal atom-electron equivalents (PAE-EE), where electron equivalents (EEs) are multivalent linkers with two distinct types of single-stranded DNA (ssDNA) ends complementary to those ssDNAs on binary programmable atom equivalents (PAEs). We derive a statistical mechanical framework for calculating the effective interaction between PAEs mediated by EEs with arbitrary valency, which quantitatively agrees with simulations using explicit EEs. Our analysis reveals an anomalous dependence of PAE-PAE interactions on the EE valency, showing that EE-mediated interactions converge at the large valency limit. Moreover, we identify an optimal EE valency that maximizes the interaction difference between targeted and non-targeted binding pairs of PAEs. These findings offer design principles for targeted self-assembly in PAE-EE systems.\",\"PeriodicalId\":21110,\"journal\":{\"name\":\"Reports on Progress in Physics\",\"volume\":\"27 1\",\"pages\":\"\"},\"PeriodicalIF\":19.0000,\"publicationDate\":\"2025-06-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Reports on Progress in Physics\",\"FirstCategoryId\":\"101\",\"ListUrlMain\":\"https://doi.org/10.1088/1361-6633/ade625\",\"RegionNum\":1,\"RegionCategory\":\"物理与天体物理\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"PHYSICS, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reports on Progress in Physics","FirstCategoryId":"101","ListUrlMain":"https://doi.org/10.1088/1361-6633/ade625","RegionNum":1,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PHYSICS, MULTIDISCIPLINARY","Score":null,"Total":0}
Designed self-assembly of programmable colloidal atom-electron equivalents
To unlock the potential for assembling complex colloidal ‘molecules’, we investigate a minimal binary system of programmable colloidal atom-electron equivalents (PAE-EE), where electron equivalents (EEs) are multivalent linkers with two distinct types of single-stranded DNA (ssDNA) ends complementary to those ssDNAs on binary programmable atom equivalents (PAEs). We derive a statistical mechanical framework for calculating the effective interaction between PAEs mediated by EEs with arbitrary valency, which quantitatively agrees with simulations using explicit EEs. Our analysis reveals an anomalous dependence of PAE-PAE interactions on the EE valency, showing that EE-mediated interactions converge at the large valency limit. Moreover, we identify an optimal EE valency that maximizes the interaction difference between targeted and non-targeted binding pairs of PAEs. These findings offer design principles for targeted self-assembly in PAE-EE systems.
期刊介绍:
Reports on Progress in Physics is a highly selective journal with a mission to publish ground-breaking new research and authoritative invited reviews of the highest quality and significance across all areas of physics and related areas. Articles must be essential reading for specialists, and likely to be of broader multidisciplinary interest with the expectation for long-term scientific impact and influence on the current state and/or future direction of a field.