芳基烃受体是溃疡性结肠炎的一个有希望的治疗靶点，它损害了hk2控制的己糖胺生物合成途径的通量，以n -糖基化依赖的方式消除NETosis

IF 13 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Journal of Advanced Research Pub Date : 2025-06-27 DOI:10.1016/j.jare.2025.06.078

Shijia Li, Jingchao Zhu, Jie Song, Li Yang, Yingfei Gong, Yue Dai, Zhifeng Wei

引用次数: 0

摘要

芳烃受体（AhR）是溃疡性结肠炎（UC）的一个有前景的治疗靶点，并在调节中性粒细胞功能中发挥作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Aryl hydrocarbon receptor, a promising therapeutic target for ulcerative colitis, impairs HK2-controlled flux of hexosamine-biosynthesis pathway to eliminate NETosis in an N-glycosylation dependent manner

The aryl hydrocarbon receptor (AhR) is a promising therapeutic target for ulcerative colitis (UC) and plays a role in regulating neutrophil function.

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来源期刊

Journal of Advanced Research Multidisciplinary-Multidisciplinary

CiteScore

21.60

自引率

0.90%

发文量

280

审稿时长

12 weeks

期刊介绍： Journal of Advanced Research (J. Adv. Res.) is an applied/natural sciences, peer-reviewed journal that focuses on interdisciplinary research. The journal aims to contribute to applied research and knowledge worldwide through the publication of original and high-quality research articles in the fields of Medicine, Pharmaceutical Sciences, Dentistry, Physical Therapy, Veterinary Medicine, and Basic and Biological Sciences. The following abstracting and indexing services cover the Journal of Advanced Research: PubMed/Medline, Essential Science Indicators, Web of Science, Scopus, PubMed Central, PubMed, Science Citation Index Expanded, Directory of Open Access Journals (DOAJ), and INSPEC.