研究交流：乳糜泻患者摄入谷蛋白后急性反应的发生率-一项回顾性研究

IF 6.7 1区医学 Q1 GASTROENTEROLOGY & HEPATOLOGY

Alimentary Pharmacology & Therapeutics Pub Date : 2025-06-29 DOI:10.1111/apt.70255

Gabriele Avino, Francesca Burlo, Mauro Perinot, Laura Badina, Grazia Di Leo, Egidio Barbi, Chiara Zanchi

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引用次数: 0

摘要

大多数乳糜泻无麸质饮食患者的麸质暴露被认为是无症状或引起慢性症状，但一些报告严重的急性反应，如呕吐、腹泻和虚弱。评估谷蛋白摄入后的急性反应。对儿童和成人患者的回顾性研究。一份问卷调查了摄入谷蛋白后的症状。221名成人和53名儿童被纳入研究；72%报告在4小时内出现症状。呕吐在儿童中最常见，腹泻在成人中最常见。无麸质饮食的患者在意外摄入麸质后可能会出现急性症状。需要对频率、触发因素和影响进行进一步研究。

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Research Communication: Prevalence of Acute Reactions After Gluten Ingestion in Patients With Coeliac Disease—A Retrospective Study

Most gluten exposures in patients with coeliac disease on gluten‐free diet were considered asymptomatic or causing chronic symptoms, but some report severe acute reactions like vomiting, diarrhoea and prostration. Assess acute reactions following gluten ingestion. Retrospective study on paediatric and adult patients. A questionnaire investigated symptoms after gluten ingestion. 221 adults and 53 children were enrolled; 72% reported symptoms within 4 h. Vomiting was most common in children, diarrhoea in adults. Patients on gluten‐free diet may experience acute symptoms after accidental gluten ingestion. Further research is needed on frequency, triggers, and implications.

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来源期刊

Alimentary Pharmacology & Therapeutics 医学-胃肠肝病学

CiteScore

15.60

自引率

7.90%

发文量

527

审稿时长

3-6 weeks

期刊介绍： Alimentary Pharmacology & Therapeutics is a global pharmacology journal focused on the impact of drugs on the human gastrointestinal and hepato-biliary systems. It covers a diverse range of topics, often with immediate clinical relevance to its readership.