撤回：MiRNA-545负调控胃癌中EMS1的致癌活性

IF 3.1 2区医学 Q2 ONCOLOGY

Cancer Medicine Pub Date : 2025-06-30 DOI:10.1002/cam4.71011

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引用次数: 0

摘要

引用本文：马敏，赵军，吴强，肖克，李生，朱红红，刘春春，谢红红，左超，“MiRNA-545负性调控EMS1在胃癌中的致癌活性”，《中国肿瘤医学》，第7期。6 (2018): 2452-2462, https://doi.org/10.1002/cam4.1520。上述文章于2018年5月7日在线发表在Wiley在线图书馆（wileyonlinelibrary.com）上，经作者同意撤回；杂志主编斯蒂芬·泰特；约翰·威利&；子有限公司由于在这篇文章中使用了被污染的细胞系，已经同意撤回。用于证明miR-545在EMS1表达中的调节作用的两种细胞系(SGC-7901 &；据报道BGC-823)被HeLa污染[1,2]，细胞系MGC-803也被HeLa污染[3,4]。因此，编辑认为本文的结论是无效的。我们没有发现作者行为不端的任何证据。参考文献[10]叶峰，陈晨，秦建军，刘建军，郑晨，“基因图谱揭示了中国使用的人类细胞系交叉污染的惊人速度”，中国生物医学工程学报，第29期，第2期。10 (2015): 4268-4272, https://doi.org/10.1096/fj.14-266718。[10]卞兴，杨振华，冯慧，孙慧，刘毅，“结合物种鉴定和STR分析对482种人类肿瘤细胞系交叉污染细胞的鉴定，科学通报，2017，第7期：9774，https://doi.org/10.1038/s41598-017-09660-w。[10]曹峰，杨振华，孙辉，白艳，胡晓霞，侯艳，卞晓霞，刘艳，“MGc80-3与HeLa细胞的体细胞杂交研究”，《国际癌症杂志》，第4期。1 (2024): 155-168, https://doi.org/10.1002/ijc.34677。[10]杨敏，何建军，夏淑娟，王勇，熊建军，廖春春，李宁，曲松，沈春春，“MGC-803细胞株混合来源的研究及其对HeLa来源的影响，人类细胞37 (2024):560-566,https://doi.org/10.1007/s13577-023-01011-4。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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RETRACTION: MiRNA-545 Negatively Regulates the Oncogenic Activity of EMS1 in Gastric Cancer

RETRACTION: M. Ma, J. Zhao, Q. Wu, K. Xiao, S. Li, H. Zhu, C. Liu, H. Xie, and C. Zuo, “ MiRNA-545 Negatively Regulates the Oncogenic Activity of EMS1 in Gastric Cancer,” Cancer Medicine 7, no. 6 (2018): 2452–2462, https://doi.org/10.1002/cam4.1520.

The above article, published online on 07 May 2018 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the authors; the journal Editor-in-Chief, Stephen Tait; and John Wiley & Sons Ltd.

The retraction has been agreed due to the use of contaminated cell lines in this article. Both the cell lines used to demonstrate the regulatory role of miR-545 in EMS1 expression (SGC-7901 & BGC-823) have been reported to be contaminated with HeLa [1, 2], as has cell line MGC-803 [3, 4]. Thus, the editors consider the conclusions of this article to be invalid.

We did not find any evidence of misconduct by the authors.

References

[1] F. Ye, C. Chen, J. Qin, J. Liu, and C. Zheng, “ Genetic Profiling Reveals an Alarming Rate of Cross-Contamination Among Human Cell Lines Used in China,” The FASEB Journal 29, no. 10 (2015): 4268–4272, https://doi.org/10.1096/fj.14-266718.

[2] X. Bian, Z. Yang, H. Feng, H. Sun, and Y. Liu, “ A Combination of Species Identification and STR Profiling Identifies Cross-contaminated Cells from 482 Human Tumor Cell Lines,” Scientific Reports 7 (2017): 9774, https://doi.org/10.1038/s41598-017-09660-w.

[3] F. Cao, H. Sun, Z. Yang, Y. Bai, X. Hu, Y. Hou, X. Bian, and Y. Liu, “ Multiple Approaches Revealed MGc80-3 as a Somatic Hybrid with HeLa Cells Rather than a Gastric Cancer Cell Line,” International Journal of Cancer 154, no. 1 (2024): 155–168, https://doi.org/10.1002/ijc.34677.

[4] M. Yang, J. He, S. Xia, Y. Wang, J. Xiong, C. Liao, N. Li, S. Qu, and C. Shen, " Investigation of the Mixed Origins of the MGC-803 Cell Line Reveals That It Is a Hybrid Cell Line Derived from HeLa," Human Cell 37 (2024): 560–566, https://doi.org/10.1007/s13577-023-01011-4.

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来源期刊

Cancer Medicine ONCOLOGY-

CiteScore

5.50

自引率

2.50%

发文量

907

审稿时长

19 weeks

期刊介绍： Cancer Medicine is a peer-reviewed, open access, interdisciplinary journal providing rapid publication of research from global biomedical researchers across the cancer sciences. The journal will consider submissions from all oncologic specialties, including, but not limited to, the following areas: Clinical Cancer Research Translational research ∙ clinical trials ∙ chemotherapy ∙ radiation therapy ∙ surgical therapy ∙ clinical observations ∙ clinical guidelines ∙ genetic consultation ∙ ethical considerations Cancer Biology: Molecular biology ∙ cellular biology ∙ molecular genetics ∙ genomics ∙ immunology ∙ epigenetics ∙ metabolic studies ∙ proteomics ∙ cytopathology ∙ carcinogenesis ∙ drug discovery and delivery. Cancer Prevention: Behavioral science ∙ psychosocial studies ∙ screening ∙ nutrition ∙ epidemiology and prevention ∙ community outreach. Bioinformatics: Gene expressions profiles ∙ gene regulation networks ∙ genome bioinformatics ∙ pathwayanalysis ∙ prognostic biomarkers. Cancer Medicine publishes original research articles, systematic reviews, meta-analyses, and research methods papers, along with invited editorials and commentaries. Original research papers must report well-conducted research with conclusions supported by the data presented in the paper.