{"title":"日本男性在机器人辅助根治性前列腺切除术前后的阴茎氧饱和度。","authors":"Ryo Sato, Toshiki Ito, Kyohei Watanabe, Yuto Matsushita, Hiromitsu Watanabe, Keita Tamura, Daisuke Motoyama, Atsushi Otsuka, Hideaki Miyake","doi":"10.21873/invivo.14033","DOIUrl":null,"url":null,"abstract":"<p><strong>Background/aim: </strong>The aim of this study was to investigate changes in penile oxygen saturation in Japanese patients before and after robot-assisted radical prostatectomy (RARP).</p><p><strong>Patients and methods: </strong>The present study included 33 Japanese patients who underwent RARP between June 2018 and February 2024. Tissue oxygen saturation (StO<sub>2</sub>) was measured in the glans, bilateral corpora, and both thighs before and after surgery using Toccare™, a tissue oximeter.</p><p><strong>Results: </strong>Nerve-sparing procedures were achieved as follows: right side, 16 patients (48.5%); left side, 11 (33.3%); bilateral, 4 (12.1%); none, 2 (6.1%). In all patients, no significant difference was observed in StO<sub>2</sub> in the bilateral thighs before and after surgery, whereas a significant decrease was noted in the glans and bilateral corpora after surgery. StO<sub>2</sub> in the glans and bilateral corpora significantly decreased in 20 patients in the right-side nerve-sparing group and 15 in the left-side nerve-sparing group, and nerve-sparing procedures did not correlate with changes in StO<sub>2</sub>.</p><p><strong>Conclusion: </strong>StO<sub>2</sub> in the glans and bilateral corpora decrease after RARP irrespective of whether a nerve-sparing procedure is performed.</p>","PeriodicalId":13364,"journal":{"name":"In vivo","volume":"39 4","pages":"2357-2362"},"PeriodicalIF":1.8000,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223666/pdf/","citationCount":"0","resultStr":"{\"title\":\"Penile Oxygen Saturation in Japanese Men Before and After Robot-assisted Radical Prostatectomy.\",\"authors\":\"Ryo Sato, Toshiki Ito, Kyohei Watanabe, Yuto Matsushita, Hiromitsu Watanabe, Keita Tamura, Daisuke Motoyama, Atsushi Otsuka, Hideaki Miyake\",\"doi\":\"10.21873/invivo.14033\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background/aim: </strong>The aim of this study was to investigate changes in penile oxygen saturation in Japanese patients before and after robot-assisted radical prostatectomy (RARP).</p><p><strong>Patients and methods: </strong>The present study included 33 Japanese patients who underwent RARP between June 2018 and February 2024. Tissue oxygen saturation (StO<sub>2</sub>) was measured in the glans, bilateral corpora, and both thighs before and after surgery using Toccare™, a tissue oximeter.</p><p><strong>Results: </strong>Nerve-sparing procedures were achieved as follows: right side, 16 patients (48.5%); left side, 11 (33.3%); bilateral, 4 (12.1%); none, 2 (6.1%). In all patients, no significant difference was observed in StO<sub>2</sub> in the bilateral thighs before and after surgery, whereas a significant decrease was noted in the glans and bilateral corpora after surgery. StO<sub>2</sub> in the glans and bilateral corpora significantly decreased in 20 patients in the right-side nerve-sparing group and 15 in the left-side nerve-sparing group, and nerve-sparing procedures did not correlate with changes in StO<sub>2</sub>.</p><p><strong>Conclusion: </strong>StO<sub>2</sub> in the glans and bilateral corpora decrease after RARP irrespective of whether a nerve-sparing procedure is performed.</p>\",\"PeriodicalId\":13364,\"journal\":{\"name\":\"In vivo\",\"volume\":\"39 4\",\"pages\":\"2357-2362\"},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2025-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12223666/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"In vivo\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.21873/invivo.14033\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"In vivo","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.21873/invivo.14033","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
Penile Oxygen Saturation in Japanese Men Before and After Robot-assisted Radical Prostatectomy.
Background/aim: The aim of this study was to investigate changes in penile oxygen saturation in Japanese patients before and after robot-assisted radical prostatectomy (RARP).
Patients and methods: The present study included 33 Japanese patients who underwent RARP between June 2018 and February 2024. Tissue oxygen saturation (StO2) was measured in the glans, bilateral corpora, and both thighs before and after surgery using Toccare™, a tissue oximeter.
Results: Nerve-sparing procedures were achieved as follows: right side, 16 patients (48.5%); left side, 11 (33.3%); bilateral, 4 (12.1%); none, 2 (6.1%). In all patients, no significant difference was observed in StO2 in the bilateral thighs before and after surgery, whereas a significant decrease was noted in the glans and bilateral corpora after surgery. StO2 in the glans and bilateral corpora significantly decreased in 20 patients in the right-side nerve-sparing group and 15 in the left-side nerve-sparing group, and nerve-sparing procedures did not correlate with changes in StO2.
Conclusion: StO2 in the glans and bilateral corpora decrease after RARP irrespective of whether a nerve-sparing procedure is performed.
期刊介绍:
IN VIVO is an international peer-reviewed journal designed to bring together original high quality works and reviews on experimental and clinical biomedical research within the frames of physiology, pathology and disease management.
The topics of IN VIVO include: 1. Experimental development and application of new diagnostic and therapeutic procedures; 2. Pharmacological and toxicological evaluation of new drugs, drug combinations and drug delivery systems; 3. Clinical trials; 4. Development and characterization of models of biomedical research; 5. Cancer diagnosis and treatment; 6. Immunotherapy and vaccines; 7. Radiotherapy, Imaging; 8. Tissue engineering, Regenerative medicine; 9. Carcinogenesis.