Sydney Tucker, Solis Winters, Emmanuel Katabaro, Matilda Mlowe, Patrick Bradshaw, Jennifer Ahern, John Colford, Laura Packel, Susan Hillis, Amon Sabasaba, Prosper Njau, Sandra I McCoy
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Adverse childhood experiences and disengagement from HIV care: a case-cohort study in Tanzania.
Adverse childhood experiences (ACEs) can have lasting, detrimental effects throughout the lifespan and may influence engagement in health care. We conducted a case-cohort study in Tanzania to estimate the association between ACEs and disengagement from HIV care 12 months after initiating antiretroviral therapy (ART) among 217 adults (26 cases and 191 sub-cohort participants). Experiencing one, two, three, and four additional ACEs was significantly associated with 28% (RRa= 1.24; 95% CI: 1.05, 1.44; p-value < 0.01), 64% (RRa=1.64; 95% CI: 1.22, 2.20), 110% (RRa=2.10; 95% CI: 1.35, 3.26), and 168% (RRa=2.68; 95% CI: 1.49, 4.38) increases in the risk of disengagement from HIV care, respectively. These findings call for integrated trauma-informed mental health services within HIV care to end HIV/AIDS as a public health threat.
期刊介绍：
AIDS Research and Therapy publishes articles on basic science, translational, clinical, social, epidemiological, behavioral and educational sciences articles focused on the treatment and prevention of HIV/AIDS, and the search for the cure. The Journal publishes articles on novel and developing treatment strategies for AIDS as well as on the outcomes of established treatment strategies. Original research articles on animal models that form an essential part of the AIDS treatment research are also considered
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