[实验中年龄相关和压力诱导的血清素水平和肺单胺氧化酶活性的变化]

Q4 Medicine
Y V Nesterov
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引用次数: 0

摘要

研究发现应激条件下肺代谢参数存在年龄相关性差异,表现为成年大鼠和老年大鼠肺单胺氧化酶活性升高,同时肺中血清素含量降低,幼鼠肺中血清素水平升高。实验表明,在正常情况下,肺部血清素水平明显与年龄相关,而肺单胺氧化酶活性仅在个体发生的晚期才明显下降。在压力下,肺组织中血清素水平和血液中血清素水平之间的高度负相关仅在老年动物中是典型的。指标变化的严重程度和方向由年龄决定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Age-related and stress-induced changes in serotonin levels and lung monoamine oxidase activity in the experiment.]

Study reveals age-related differences in lung metabolism parameters under stress, they are manifested in an increase in the activity of lung monoamine oxidase with a simultaneous decrease in the content of serotonin in the lungs in adult and old rats and an increase in the level of serotonin in young animals. Experiments have shown a significant age-related increase in the level of serotonin in the lungs in normal conditions and a pronounced decrease in the activity of lung monoamine oxidase only at a late stage of ontogenesis. A high negative correlation between the level of serotonin in the lung tissue and blood under stress is typical only for old animals. The severity and direction of changes in indicators are determined by age.

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CiteScore
0.50
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