骨板研究综述:现状与未来方向。

IF 3.6 4区 医学 Q2 ENGINEERING, BIOMEDICAL
Gourav Sardana, Subrata Bandhu Ghosh, Sanchita Bandyopadhyay-Ghosh
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引用次数: 0

摘要

本文深入介绍了用于骨科骨板的工程材料的机械、化学和生物特性,以及它们的设计和制造方法。本文综述了用于治疗骨折和骨异常的各种骨板材料的优缺点。金属接骨板由于其优异的力学性能,传统上被用于骨折固定。然而,机械性能的不匹配和金属骨板的高密度可导致应力屏蔽和不愈合,通常需要翻修手术。这些挑战是在审查中强调,然后探讨了聚合物板的潜力,以克服这些问题。然而,聚合物骨板的机械性能不足,往往需要开发具有患者特异性、生物相容性和易于定制的复合骨板。讨论了这一领域的新兴研究计划。文章进一步阐述了各种制作工艺及其对骨板表面性能的影响。回顾了内固定装置的传统加工工艺和用于制造患者特定的定制骨板的3D打印方法。文章最后评价了目前与骨板技术相关的进展和预期的发展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A critical review on bone plates: state of the art and future directions.

The article provides an in-depth overview of the mechanical, chemical, and biological properties of engineering materials used for orthopedic bone plates, along with their designs and fabrication methods. This review addresses the benefits and drawbacks of various materials that have been utilized as bone plates for the treatment of fractures and bone abnormalities. Due to their excellent mechanical properties, metallic bone plates have traditionally been employed for bone fracture fixation. However, the mismatch in mechanical properties and high density of metallic bone plates can lead to stress shielding and non-union, often requiring revision surgeries. These challenges are highlighted in the review, which then explores the potential of polymeric plates to overcome such issues. Nevertheless, the insufficient mechanical performance of polymeric bone plates often necessitates the development of composite bone plates that are patient-specific, biocompatible, and easily tailorable. Emerging research initiatives in this area are discussed. The article further elaborates on various fabrication processes and their impact on the surface properties of bone plates. Both conventional machining processes for internal fixation devices and 3D printing methods for fabricating patient-specific, customized bone plates are reviewed. The paper concludes by evaluating current advancements and anticipated developments related to bone plate technology.

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来源期刊
Journal of Biomaterials Science, Polymer Edition
Journal of Biomaterials Science, Polymer Edition 工程技术-材料科学:生物材料
CiteScore
7.10
自引率
5.60%
发文量
117
审稿时长
1.5 months
期刊介绍: The Journal of Biomaterials Science, Polymer Edition publishes fundamental research on the properties of polymeric biomaterials and the mechanisms of interaction between such biomaterials and living organisms, with special emphasis on the molecular and cellular levels. The scope of the journal includes polymers for drug delivery, tissue engineering, large molecules in living organisms like DNA, proteins and more. As such, the Journal of Biomaterials Science, Polymer Edition combines biomaterials applications in biomedical, pharmaceutical and biological fields.
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