用2-[18F]FDG-PET/CT影像学检查多发性骨髓瘤早期异常单侧弥漫性肾累及髓外。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-10-01 Epub Date: 2025-03-17 DOI:10.1097/RLU.0000000000005847

Bastien Jamet, Cyrille Touzeau, Chloe Antier, Philippe Moreau, Françoise Kraeber-Bodéré

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引用次数: 0

摘要

2-[18F]氟脱氧葡萄糖-正电子发射断层扫描与计算机断层扫描（2-[18F]FDG-PET/CT）在多发性骨髓瘤（MM）中可以发现髓外疾病（EMD），这在最初的检查中是很少的。我们在此首次报道罕见的2-[18F]FDG-PET/CT成像结果，一名63岁女性，新诊断为MM和单侧弥漫性肾EMD，显示肾脏体积明显增加，双侧肾皮质摄取强烈/弥漫性，未见尿排泄腔，经肾活检证实。本病例强调了与软组织结节性浆细胞瘤病变的典型影像模式不同的弥漫性器官受累的可能性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Unusual Sole Extramedullary Diffuse Kidney Involvement in Multiple Myeloma Initial Workup Using 2-[ 18 F]FDG-PET/CT Imaging.

2-[ 18 F]fluorodeoxyglucose-positron emission tomography with computed tomography (2-[ 18 F]FDG-PET/CT) in multiple myeloma (MM) allows the detection of extramedullary disease (EMD), which is scarce at initial workup. We report here for the first time uncommon 2-[ 18 F]FDG-PET/CT imaging results of a 63-year-old woman with newly diagnosed MM and sole diffuse kidney EMD revealed by a significantly increased renal volume and intense/diffuse bilateral renal cortical uptake without visualization of the urinary excretory cavities then confirmed by kidney biopsy. This case highlights the possibility of a diffuse organ involvement different from the typical imaging pattern of nodular plasmacytoma lesions in soft tissues.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.