注意两点均方位移。

IF 2.9 3区 化学 Q3 CHEMISTRY, PHYSICAL
Soft Matter Pub Date : 2025-06-27 DOI:10.1039/d5sm00555h
Naoya Katayama, Takahiro Sakaue
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引用次数: 0

摘要

当感兴趣的探针分子在随机运动下嵌入衬底或聚集体时,需要依靠所谓的两点均方位移(MSD)测量来提取探针的固有迁移率。我们讨论了两个版本,基于相对矢量的时间序列或两个探针之间的距离,并总结了它们与标准MSD相比的基本特性。我们还提出了一种从两点MSD中提取(i)位移统计中的非高斯性和(ii)探针之间的运动相关性的方法。这些结果不仅适用于独立探针,也适用于长聚合物内的分子内探针,可用于定量活细胞核中染色质位点的动力学。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Note on two-point mean square displacement.

When probe molecules of interest are embedded in a substrate or aggregate under stochastic motion, one needs to rely on the so-called two-point mean square displacement (MSD) measurement to extract the intrinsic mobility of the probes. We discuss two versions, based on the time series of relative vector or distance between two probes, and summarize their basic properties compared to the standard MSD. We also propose a way to extract (i) the non-Gaussianity in the displacement statistics and (ii) the motional correlation between probes from the two-point MSD. The results are presented not only for independent probes, but also for intramolecular probes within a long polymer, which could be useful in quantifying the dynamics of chromatin loci in a living cell nucleus.

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来源期刊
Soft Matter
Soft Matter 工程技术-材料科学:综合
CiteScore
6.00
自引率
5.90%
发文量
891
审稿时长
1.9 months
期刊介绍: Soft Matter is an international journal published by the Royal Society of Chemistry using Engineering-Materials Science: A Synthesis as its research focus. It publishes original research articles, review articles, and synthesis articles related to this field, reporting the latest discoveries in the relevant theoretical, practical, and applied disciplines in a timely manner, and aims to promote the rapid exchange of scientific information in this subject area. The journal is an open access journal. The journal is an open access journal and has not been placed on the alert list in the last three years.
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