核医学部门病人剂量和辐射风险评估

IF 2.8 3区物理与天体物理 Q3 CHEMISTRY, PHYSICAL

Radiation Physics and Chemistry Pub Date : 2025-06-28 DOI:10.1016/j.radphyschem.2025.113120

Ali Aamry, Jaber Aseiri, Fatimah Daghas, Hussin Aamri, Hassan Salah, Alkhybari, Alkhorayef, Nissren Tamam, David Bradley, Abdelmoneim Sulieman

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引用次数: 0

摘要

本研究评估患者在甲状旁腺SPECT/CT检查过程中接受的辐射剂量，并推断敏感器官的相关癌症风险。对接受SPECT/CT检查的20例患者进行辐射剂量评估，其中12例女性（60%）和8例男性（40%）。采用99mTc-甲氧基异丁基异硝基腈（MIBI）（AA, MBq）的给药活性和外部CT程序的剂量确定患者的器官和有效剂量。所有程序均在沙特阿拉伯利雅得的沙特国王医疗城使用双混合系统（GE和西门子SPECT/CT）。每次SPECT/CT检查的总体平均有效剂量（mSv）为6.0（3.1至7.5）。平均每3400次SPECT/CT检查发生癌症的概率就超过一次。CT照射占总有效剂量的89.1%，而外部照射（CT照射）占10.9%。由于放射性核素的优化使用和CT图像采集方案，每次SPECT/CT检查的剂量低于大多数文献报道。本研究结果对了解医学领域的辐射安全和成像程序具有重要意义。

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Assessment of Patient dose and radiation risks at a nuclear medicine department

This study evaluates the radiation dose received by patients during the parathyroid SPECT/CT procedure and extrapolates the associated cancer risks for sensitive organs. The radiation doses were assessed for 20 patients, 12 females (60%) and eight males (40%), who underwent the SPECT/CT procedure. The organs of the patients and the effective dose were determined using the administered activity of 99mTc--methoxyisobutylisonitrilec (MIBI) (AA, MBq) and the dose from the external CT procedure. All procedures utilized two-hybrid systems (GE and Siemens SPECT/CT) at King Saud Medical City, Riyadh, Saudi Arabia. The overall average and range of the effective dose (mSv) is 6.0 (3.1 to 7.5) per SPECT/CT procedure. The probability of cancer risk is oner per 3400 SPECT/CT procedure, on average. The CT procedures contributed 89.1 % of the total effective dose, while 10.9 % resulted from external exposure (CT exposure). The dose per SPECT/CT examination is lower than most reported literature due to the optimised usage of radionuclides’ and CT image acquisition protocol. The findings of this study are significant in understanding the radiation safety and imaging procedures in the medical field.

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来源期刊

Radiation Physics and Chemistry 化学-核科学技术

CiteScore

5.60

自引率

17.20%

发文量

574

审稿时长

12 weeks

期刊介绍： Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.