Gabriele Pagani , Francesco Bassani , Paola Mirri , Bianca Osnaghi , Elena Delmastro , Stefano Rusconi
{"title":"异戊康唑成功治疗土壤污染外伤致早期无精子孢子虫感染1例","authors":"Gabriele Pagani , Francesco Bassani , Paola Mirri , Bianca Osnaghi , Elena Delmastro , Stefano Rusconi","doi":"10.1016/j.idcr.2025.e02294","DOIUrl":null,"url":null,"abstract":"<div><div>Scedosporium apiospermium, a rare fungal pathogen from soil and stagnant water, can cause invasive infections, particularly in immunocompromised patients. An 83-year-old male with a soil-contaminated traumatic wound developed persistent inflammation despite antibiotic therapy. <em>Scedosporium apiospermium</em> was identified, and systemic isavuconazole led to significant wound improvement after eight weeks. This case emphasizes the need to consider fungal infections in traumatic wounds. Isavuconazole was effective and safe, offering a valuable alternative to voriconazole</div></div>","PeriodicalId":47045,"journal":{"name":"IDCases","volume":"41 ","pages":"Article e02294"},"PeriodicalIF":1.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Early Scedosporium apiospermium infection of a soil-contaminated traumatic injury successfully treated with isavuconazole: A case report\",\"authors\":\"Gabriele Pagani , Francesco Bassani , Paola Mirri , Bianca Osnaghi , Elena Delmastro , Stefano Rusconi\",\"doi\":\"10.1016/j.idcr.2025.e02294\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Scedosporium apiospermium, a rare fungal pathogen from soil and stagnant water, can cause invasive infections, particularly in immunocompromised patients. An 83-year-old male with a soil-contaminated traumatic wound developed persistent inflammation despite antibiotic therapy. <em>Scedosporium apiospermium</em> was identified, and systemic isavuconazole led to significant wound improvement after eight weeks. This case emphasizes the need to consider fungal infections in traumatic wounds. Isavuconazole was effective and safe, offering a valuable alternative to voriconazole</div></div>\",\"PeriodicalId\":47045,\"journal\":{\"name\":\"IDCases\",\"volume\":\"41 \",\"pages\":\"Article e02294\"},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2025-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IDCases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214250925001507\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IDCases","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214250925001507","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Early Scedosporium apiospermium infection of a soil-contaminated traumatic injury successfully treated with isavuconazole: A case report
Scedosporium apiospermium, a rare fungal pathogen from soil and stagnant water, can cause invasive infections, particularly in immunocompromised patients. An 83-year-old male with a soil-contaminated traumatic wound developed persistent inflammation despite antibiotic therapy. Scedosporium apiospermium was identified, and systemic isavuconazole led to significant wound improvement after eight weeks. This case emphasizes the need to consider fungal infections in traumatic wounds. Isavuconazole was effective and safe, offering a valuable alternative to voriconazole
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