Fatima EL. Kamari , Abdelghani Bouchyoua , Jihane El Amrani , Anjoud Harmouzi , Nor El Houda Tahiri , Amal Sbai , Mohamed El-Shazly , Shaza H. Aly , Abdelfettah El Moussaoui , Badiaa Lyoussi , Driss Ousaaid
{"title":"花楸精油的化学成分、抗氧化及抗菌活性","authors":"Fatima EL. Kamari , Abdelghani Bouchyoua , Jihane El Amrani , Anjoud Harmouzi , Nor El Houda Tahiri , Amal Sbai , Mohamed El-Shazly , Shaza H. Aly , Abdelfettah El Moussaoui , Badiaa Lyoussi , Driss Ousaaid","doi":"10.1016/j.bse.2025.105076","DOIUrl":null,"url":null,"abstract":"<div><div>Medicinal plants constitute an inexhaustible reservoir of phytochemicals with multiple biological properties that have been evoked traditionally and proven scientifically. The current study was conducted to assess the volatile profile of <em>Cladanthus mixtus</em> essential oil collected from the Guercif region for its aromatic constituents using GC/MS, as well as its antioxidant and antibacterial activities. Chromatographic analysis revealed that the most abundant volatile compound was <em>α</em>-pinene (77.30 %). In the DPPH, FRAP, and ABTS assays, the IC<sub>50</sub> values at 0.41 ± 0.02 mg/ml, 0.98 ± 0.06 mg/ml, and 2.01 ± 0.04 mg/ml, respectively. The essential oil was also effective against <em>S. aureus</em> and <em>C. koseri</em> with MIC value of 0.187 mg/ml for both bacterial strains. The present investigation indicates that <em>C. mixtus</em> can be a potential natural source of bioactive compounds for product-grade antioxidants for pharmaceutical applications.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"123 ","pages":"Article 105076"},"PeriodicalIF":1.4000,"publicationDate":"2025-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Chemical composition, antioxidant, and antibacterial activities of Cladanthus mixtus essential oil\",\"authors\":\"Fatima EL. Kamari , Abdelghani Bouchyoua , Jihane El Amrani , Anjoud Harmouzi , Nor El Houda Tahiri , Amal Sbai , Mohamed El-Shazly , Shaza H. Aly , Abdelfettah El Moussaoui , Badiaa Lyoussi , Driss Ousaaid\",\"doi\":\"10.1016/j.bse.2025.105076\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Medicinal plants constitute an inexhaustible reservoir of phytochemicals with multiple biological properties that have been evoked traditionally and proven scientifically. The current study was conducted to assess the volatile profile of <em>Cladanthus mixtus</em> essential oil collected from the Guercif region for its aromatic constituents using GC/MS, as well as its antioxidant and antibacterial activities. Chromatographic analysis revealed that the most abundant volatile compound was <em>α</em>-pinene (77.30 %). In the DPPH, FRAP, and ABTS assays, the IC<sub>50</sub> values at 0.41 ± 0.02 mg/ml, 0.98 ± 0.06 mg/ml, and 2.01 ± 0.04 mg/ml, respectively. The essential oil was also effective against <em>S. aureus</em> and <em>C. koseri</em> with MIC value of 0.187 mg/ml for both bacterial strains. The present investigation indicates that <em>C. mixtus</em> can be a potential natural source of bioactive compounds for product-grade antioxidants for pharmaceutical applications.</div></div>\",\"PeriodicalId\":8799,\"journal\":{\"name\":\"Biochemical Systematics and Ecology\",\"volume\":\"123 \",\"pages\":\"Article 105076\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-06-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biochemical Systematics and Ecology\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0305197825001255\",\"RegionNum\":4,\"RegionCategory\":\"生物学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"BIOCHEMISTRY & MOLECULAR BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochemical Systematics and Ecology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0305197825001255","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
Chemical composition, antioxidant, and antibacterial activities of Cladanthus mixtus essential oil
Medicinal plants constitute an inexhaustible reservoir of phytochemicals with multiple biological properties that have been evoked traditionally and proven scientifically. The current study was conducted to assess the volatile profile of Cladanthus mixtus essential oil collected from the Guercif region for its aromatic constituents using GC/MS, as well as its antioxidant and antibacterial activities. Chromatographic analysis revealed that the most abundant volatile compound was α-pinene (77.30 %). In the DPPH, FRAP, and ABTS assays, the IC50 values at 0.41 ± 0.02 mg/ml, 0.98 ± 0.06 mg/ml, and 2.01 ± 0.04 mg/ml, respectively. The essential oil was also effective against S. aureus and C. koseri with MIC value of 0.187 mg/ml for both bacterial strains. The present investigation indicates that C. mixtus can be a potential natural source of bioactive compounds for product-grade antioxidants for pharmaceutical applications.
期刊介绍:
Biochemical Systematics and Ecology is devoted to the publication of original papers and reviews, both submitted and invited, in two subject areas: I) the application of biochemistry to problems relating to systematic biology of organisms (biochemical systematics); II) the role of biochemistry in interactions between organisms or between an organism and its environment (biochemical ecology).
In the Biochemical Systematics subject area, comparative studies of the distribution of (secondary) metabolites within a wider taxon (e.g. genus or family) are welcome. Comparative studies, encompassing multiple accessions of each of the taxa within their distribution are particularly encouraged. Welcome are also studies combining classical chemosystematic studies (such as comparative HPLC-MS or GC-MS investigations) with (macro-) molecular phylogenetic studies. Studies that involve the comparative use of compounds to help differentiate among species such as adulterants or substitutes that illustrate the applied use of chemosystematics are welcome. In contrast, studies solely employing macromolecular phylogenetic techniques (gene sequences, RAPD studies etc.) will be considered out of scope. Discouraged are manuscripts that report known or new compounds from a single source taxon without addressing a systematic hypothesis. Also considered out of scope are studies using outdated and hard to reproduce macromolecular techniques such as RAPDs in combination with standard chemosystematic techniques such as GC-FID and GC-MS.