私人保险和活体肾移植之间的关系:平价医疗法案作为一个自然实验。

Kathleen Perry, Miko Yu, Joel T Adler, Lindsey M Maclay, David C Cron, Sumit Mohan, Syed A Husain
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引用次数: 0

摘要

背景:私人保险覆盖率与较高的活体供体肾移植(LDKT)率相关,但这是否可归因于混杂因素尚不清楚。目的:研究私营医疗保险可及性增加与LDKT之间的关系。方法:采用美国移植登记资料进行回顾性队列研究。我们确定了年龄在22-29岁之间的候选者,这些候选者在2005-2014年期间等待进行仅肾移植,不包括先前的移植接受者和数据缺失者。我们将受政策变化影响的候选人(22-25岁)与未受政策变化影响的候选人(26-29岁)的死亡和退市作为竞争事件,计算了有私人保险的人与其他保险的人在等待名单后LDKT的风险(平价医疗法案(ACA)前与ACA后)。结果:共纳入13817例患者,其中22-25岁占46%,26-29岁占54%。在22-25岁的候选人中,与aca前的候选人相比,aca后的候选人更有可能拥有私人保险(42%对35%),但26-29岁的候选人在不同时代的私人保险覆盖率没有差异。在调整后的竞争风险回归中,与aca前相比,22-25岁的私人保险患者在aca后接受LDKT的可能性更小[风险比(HR) = 0.88, 95%CI: 0.78-1.00], 22-25岁的其他保险类型患者也是如此(HR = 0.80, 95%CI: 0.69-0.92)。这些关联在26-29岁的候选人中未见。结论:22-25岁的候选人在aca后更有可能拥有私人保险,而LDKT的比例没有增加。保险和LDKT之间的关联可能归因于残留混淆。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Association between private insurance and living donor kidney transplant: Affordable Care Act as a natural experiment.

Background: Private insurance coverage is associated with higher rates of living donor kidney transplantation (LDKT) but whether this is attributable to confounding is not known.

Aim: To study the association between increased access to private health insurance and LDKT.

Methods: Retrospective cohort study using United States transplant registry data. We identified incident candidates aged 22-29 years who were waitlisted for a kidney-only transplant from 2005-2014, excluding prior transplant recipients and those with missing data. We calculated the hazard of LDKT after waitlisting for those with private insurance vs other insurance pre-Affordable Care Act (ACA) vs post-ACA, using death and delisting as competing events, for candidates affected by the policy change (age 22-25 years) vs those who were not (age 26-29 years).

Results: A total of 13817 candidates were included, of whom 46% were age 22-25 years and 54% were age 26-29 years. Among candidates aged 22-25 years at listing, those listed post-ACA were more likely to have private insurance compared to those listed pre-ACA (42% vs 35%), but there was no difference in private insurance coverage between eras among candidates aged 26-29 years at listing. In adjusted competing risk regression, privately insured patients age 22-25 years were less likely to receive a LDKT post-ACA compared to pre-ACA [hazard ratio (HR) = 0.88, 95%CI: 0.78-1.00], as were those aged 22-25 years old with other insurance types (HR = 0.80, 95%CI: 0.69-0.92). These associations were not seen among candidates age 26-29 years.

Conclusion: Candidates age 22-25 years were likelier to have private insurance post-ACA, without an increased rate in LDKT. Demonstrations of associations between insurance and LDKT are likely attributable to residual confounding.

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