Oladipo Ayoola Olanipekun, Stephen Olawale Oguntola, Adekunle Kayode Agoke, Adedayo Hakeem Oyebanji, Olamide Nelson Ogidan, Akinola Akinmade, Dhirendrakumar Jayantilal Dave, Anthony Olubunmi Akintomide, Michael Sanusi, Kamar Tayo Adeleke
{"title":"在尼日利亚阿多埃基蒂的阿布德多系统医院转诊接受冠状动脉造影的患者中冠状动脉疾病的模式和相关因素:一项描述性横断面研究。","authors":"Oladipo Ayoola Olanipekun, Stephen Olawale Oguntola, Adekunle Kayode Agoke, Adedayo Hakeem Oyebanji, Olamide Nelson Ogidan, Akinola Akinmade, Dhirendrakumar Jayantilal Dave, Anthony Olubunmi Akintomide, Michael Sanusi, Kamar Tayo Adeleke","doi":"10.11604/pamj.2025.50.55.45726","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>coronary artery disease (CAD) is a common cardiovascular disease (CVD) and a notable cause of mortality worldwide. Angiographic diagnosis of CAD is not widely available in sub-Saharan Africa. We assessed the pattern and correlates of CAD among patients referred for coronary angiography in Ado-Ekiti, Nigeria.</p><p><strong>Methods: </strong>patients with clinical suspicion of CAD who were referred for coronary angiography at Afe Babalola University Multi-System Hospital (AMSH) from August 2019 to December 2020 were recruited into the study after a written informed consent was obtained. Serum fasting lipids, electrolytes, urea and creatinine and erythrocyte sedimentation rate (ESR) were assessed. All patients had coronary angiography.</p><p><strong>Results: </strong>forty-six (46) patients were recruited into the study. The mean age among patients who had CAD was 52.12 years (±10.34). There were 15 (32.6%) females in the study population. CAD was confirmed in 18/46 (39.1%) patients. Triple vessel disease (TVD) was seen in 9/18 (50.0%) of patients who had CAD, hence, the most prevalent CAD disease pattern. ESR was significantly prolonged among patients who had CAD compared to patients who did not have CAD on univariate analysis while diabetes mellitus was an independent risk factor for CAD and conferred a greater than 7-fold risk for CAD (aOR: 7.28, 95% CI 1.15-46.16; p = 0.035).</p><p><strong>Conclusion: </strong>diabetes mellitus was an independent risk factor for CAD. Triple vessel disease was the most common pattern of CAD in our study. ESR was associated with CAD.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"50 ","pages":"55"},"PeriodicalIF":0.9000,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188011/pdf/","citationCount":"0","resultStr":"{\"title\":\"Pattern and correlates of coronary artery disease among patients referred for coronary angiography at Abuad Multisystem Hospital, Ado-Ekiti, Nigeria: a descriptive cross-sectional study.\",\"authors\":\"Oladipo Ayoola Olanipekun, Stephen Olawale Oguntola, Adekunle Kayode Agoke, Adedayo Hakeem Oyebanji, Olamide Nelson Ogidan, Akinola Akinmade, Dhirendrakumar Jayantilal Dave, Anthony Olubunmi Akintomide, Michael Sanusi, Kamar Tayo Adeleke\",\"doi\":\"10.11604/pamj.2025.50.55.45726\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>coronary artery disease (CAD) is a common cardiovascular disease (CVD) and a notable cause of mortality worldwide. Angiographic diagnosis of CAD is not widely available in sub-Saharan Africa. We assessed the pattern and correlates of CAD among patients referred for coronary angiography in Ado-Ekiti, Nigeria.</p><p><strong>Methods: </strong>patients with clinical suspicion of CAD who were referred for coronary angiography at Afe Babalola University Multi-System Hospital (AMSH) from August 2019 to December 2020 were recruited into the study after a written informed consent was obtained. Serum fasting lipids, electrolytes, urea and creatinine and erythrocyte sedimentation rate (ESR) were assessed. All patients had coronary angiography.</p><p><strong>Results: </strong>forty-six (46) patients were recruited into the study. The mean age among patients who had CAD was 52.12 years (±10.34). There were 15 (32.6%) females in the study population. CAD was confirmed in 18/46 (39.1%) patients. Triple vessel disease (TVD) was seen in 9/18 (50.0%) of patients who had CAD, hence, the most prevalent CAD disease pattern. ESR was significantly prolonged among patients who had CAD compared to patients who did not have CAD on univariate analysis while diabetes mellitus was an independent risk factor for CAD and conferred a greater than 7-fold risk for CAD (aOR: 7.28, 95% CI 1.15-46.16; p = 0.035).</p><p><strong>Conclusion: </strong>diabetes mellitus was an independent risk factor for CAD. Triple vessel disease was the most common pattern of CAD in our study. ESR was associated with CAD.</p>\",\"PeriodicalId\":48190,\"journal\":{\"name\":\"Pan African Medical Journal\",\"volume\":\"50 \",\"pages\":\"55\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-05-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188011/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Pan African Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.11604/pamj.2025.50.55.45726\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pan African Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.11604/pamj.2025.50.55.45726","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
摘要
简介:冠状动脉疾病(CAD)是一种常见的心血管疾病(CVD),是世界范围内死亡率最高的疾病之一。在撒哈拉以南非洲,冠心病的血管造影诊断并不广泛。我们评估了在尼日利亚Ado-Ekiti接受冠状动脉造影的患者中冠心病的模式和相关因素。方法:2019年8月至2020年12月在阿菲巴巴罗拉大学多系统医院(AMSH)转诊的临床疑似CAD患者在获得书面知情同意后加入研究。测定空腹血脂、电解质、尿素、肌酐和红细胞沉降率(ESR)。所有患者均行冠状动脉造影。结果:46例患者被纳入研究。冠心病患者的平均年龄为52.12岁(±10.34岁)。研究人群中有15名女性(32.6%)。46例患者中有18例(39.1%)确诊CAD。三支血管病变(TVD)见于9/18(50.0%)的CAD患者,因此是最常见的CAD疾病类型。单因素分析显示,冠心病患者的ESR明显延长,而糖尿病是冠心病的独立危险因素,并赋予冠心病7倍以上的风险(aOR: 7.28, 95% CI 1.15-46.16;P = 0.035)。结论:糖尿病是冠心病的独立危险因素。三支血管病变是我们研究中最常见的冠心病类型。ESR与CAD相关。
Pattern and correlates of coronary artery disease among patients referred for coronary angiography at Abuad Multisystem Hospital, Ado-Ekiti, Nigeria: a descriptive cross-sectional study.
Introduction: coronary artery disease (CAD) is a common cardiovascular disease (CVD) and a notable cause of mortality worldwide. Angiographic diagnosis of CAD is not widely available in sub-Saharan Africa. We assessed the pattern and correlates of CAD among patients referred for coronary angiography in Ado-Ekiti, Nigeria.
Methods: patients with clinical suspicion of CAD who were referred for coronary angiography at Afe Babalola University Multi-System Hospital (AMSH) from August 2019 to December 2020 were recruited into the study after a written informed consent was obtained. Serum fasting lipids, electrolytes, urea and creatinine and erythrocyte sedimentation rate (ESR) were assessed. All patients had coronary angiography.
Results: forty-six (46) patients were recruited into the study. The mean age among patients who had CAD was 52.12 years (±10.34). There were 15 (32.6%) females in the study population. CAD was confirmed in 18/46 (39.1%) patients. Triple vessel disease (TVD) was seen in 9/18 (50.0%) of patients who had CAD, hence, the most prevalent CAD disease pattern. ESR was significantly prolonged among patients who had CAD compared to patients who did not have CAD on univariate analysis while diabetes mellitus was an independent risk factor for CAD and conferred a greater than 7-fold risk for CAD (aOR: 7.28, 95% CI 1.15-46.16; p = 0.035).
Conclusion: diabetes mellitus was an independent risk factor for CAD. Triple vessel disease was the most common pattern of CAD in our study. ESR was associated with CAD.