[泌尿生殖系统肿瘤分子残留病检测现状]。

Q4 Medicine
Taigo Kato
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引用次数: 0

摘要

包括机器人手术在内的外科手术的最新进展改善了可切除实体瘤的临床结果。尽管术前化疗通常用于高危癌症,但术后复发的风险仍然是一个关键问题。到目前为止,通过定期影像学检查监测复发情况;然而,分子残留病(MRD)作为早期发现微小癌变的手段受到了广泛关注。随着新一代测序技术在循环肿瘤DNA(ctDNA)分析方面的快速发展,MRD检测正在成为预测多种类型癌症复发的有前途的工具。因此,在本文中,我们讨论了MRD检测在泌尿生殖系统癌症中的现状及其对未来治疗策略的潜在影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Current Status of Molecular Residual Disease Testing in Genitourinary Cancers].

Recent advancements of surgery including robotic surgery have improved the clinical outcomes of resectable solid tumors. Although preoperative chemotherapy is often performed for high-risk cancers, the risk of postoperative recurrence remains a critical issue. So far, recurrence has been monitored through periodic imaging tests; however, molecular residual disease (MRD)has caught much attention as the means to detect minimal cancerous lesions at an earlier stage. With the rapid advancements in circulating tumor DNA(ctDNA)analysis using next-generation sequencing, MRD testing is emerging as a promising tool for predicting recurrence in multiple types of cancer. Thus, in this article, we discuss the current status of MRD testing in urogenital cancers and its potential impact on future treatment strategies.

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CiteScore
0.20
自引率
0.00%
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