马上下眼睑眼睑下灌洗系统相关并发症:一项73例前瞻性随机研究(2015-2024)。

IF 2.4 2区 农林科学 Q1 VETERINARY SCIENCES
Annabelle E Graham, Harry B Carslake, Fernando Malalana
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引用次数: 0

摘要

背景:睑下灌洗(SPL)系统的最佳位置缺乏证据。目的:比较上眼睑中央和下眼睑内侧的SPL系统在住院患者中的并发症发生率和类型。研究设计:前瞻性、随机化治疗试验。方法:纳入2015年2月至2024年1月期间使用SPL系统进行眼科治疗的马匹,如果眼部病理不需要在特定位置放置SPL系统。他们用抛硬币来确定地点。至少每天监测SPL系统,并将并发症定义为主要并发症(足板从穹窿移位±角膜溃疡;踏板丢失;眼睑感染/脓肿形成)或轻微(缝线/胶带丢失;眼睑肿胀;渗漏或管子破裂;注射口丢失;缝合处皮下肿胀/脓肿)。数据采用逻辑回归分析。结果:68匹马的73个SPL系统被纳入,其中38个(52%)位于上眼睑,35个(48%)位于下眼睑,中位(IQR)持续时间为13(8-16)天。在所有SPL系统中发生69例并发症(上SPL系统37例(54%),下SPL系统32例(46%)),占44/73(60%)。发生主要并发症2例(2/69;3%)和10个上SPL系统(10/69;14%)。最常见的主要并发症是灌洗钢板从结膜穹窿移位(7/69;10%)。最常见的小并发症是缝线或蝶带丢失(21/69;30%)。氯霉素治疗组(OR = 0.3;95% ci: 0.09-0.8;p = 0.02)或交联修饰透明质酸(or = 3.9;95% ci: 1.2-13.3;多变量分析P = 0.03)与并发症相关。多变量分析显示,上层系统为5.1 (95% CI: 1.0-25.7;p = 0.05)较低声压级系统更容易出现主要并发症。主要限制:研究规模小。结论:SPL系统的位置对所有并发症均无影响,但主要并发症多见于上睑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Complications associated with subpalpebral lavage systems in upper and lower equine eyelids: A prospective, randomised study in 73 cases (2015-2024).

Background: Evidence for optimal location of subpalpebral lavage (SPL) systems is lacking.

Objectives: To compare the rate and types of complications with SPL systems located in central upper- compared with medial lower-eyelid in hospitalised patients.

Study design: Prospective, randomised treatment trial.

Methods: Horses admitted for ophthalmic treatment using an SPL system from February 2015 to January 2024 were included if ocular pathology did not necessitate SPL system placement in a specific location. Coin toss was used to determine location. SPL systems were monitored at least daily, and complications were defined as major (displacement of footplate from the fornix ± corneal ulceration; loss of footplate; eyelid infection/abscess formation) or minor (loss of suture/tape; palpebral swelling; leakage or tube rupture; loss of injection port; subcutaneous swelling/abscess at suture site). Data were analysed using logistic regression.

Results: Seventy-three SPL systems in 68 horses were included, with 38 (52%) located in the upper and 35 (48%) in the lower eyelid, for a median (IQR) duration of 13 (8-16) days. Sixty-nine complications (37 (54%) in upper and 32 (46%) in lower SPL systems) occurred in 44/73 (60%) of all SPL systems. Major complications occurred with 2 lower (2/69; 3%) and 10 upper SPL systems (10/69;14%). The most common major complication was displacement of the lavage footplate from the conjunctival fornix (7/69; 10%). The most common minor complication was loss of suture or butterfly tape (21/69; 30%). Treatment with chloramphenicol (OR = 0.3; 95% CI: 0.09-0.8; p = 0.02) or cross-linked modified hyaluronic acid (OR = 3.9; 95% CI: 1.2-13.3; p = 0.03) was associated with any complication on multivariable analysis. Multivariable analysis showed that upper systems were 5.1 (95% CI: 1.0-25.7; p = 0.05) more likely to have a major complication than lower SPL systems.

Main limitations: Small study size.

Conclusions: SPL system location had no effect on all complications, but major complications were more common in those placed in the upper lid.

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来源期刊
Equine Veterinary Journal
Equine Veterinary Journal 农林科学-兽医学
CiteScore
5.10
自引率
13.60%
发文量
161
审稿时长
6-16 weeks
期刊介绍: Equine Veterinary Journal publishes evidence to improve clinical practice or expand scientific knowledge underpinning equine veterinary medicine. This unrivalled international scientific journal is published 6 times per year, containing peer-reviewed articles with original and potentially important findings. Contributions are received from sources worldwide.
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