基于XGBoost和shap的韩国绝经后妇女高血压分型危险因素分析

IF 3.8 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Hojeong Kim, Mavlonbek Khomidov, Jong-Ha Lee
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引用次数: 0

摘要

在绝经后妇女中,高血压的患病率急剧上升,强调了其预防的重要性。这种增加的风险突出表明,迫切需要为这一人群专门设计有效的预防战略。为了解决这一问题,本研究旨在利用可解释的人工智能(XAI)和机器学习(ML)技术,确定导致绝经后妇女高血压的容易测量的危险因素。本研究采用XGBoost、SVM和ANN方法,对3289名年龄在55-79岁的绝经后韩国女性的健康检查数据进行分类分析,这些数据提取自2022-2023年韩国国民健康保险服务(KNHIS)数据库。XGBoost是高血压分类最有效的模型(AUC: 92.12%, MCC: 0.71)。基于Shapley加性解释的特征重要性确定年龄和腰围(WC)是高血压最重要的危险因素。在这项研究中,血压随WC的变化而升高,WC是一个可改变的危险因素。这些发现表明,应更严格地管理WC,以预防绝经后妇女的高血压。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
XGBoost and SHAP-Based Analysis of Risk Factors for Hypertension Classification in Korean Postmenopausal Women.

In postmenopausal women, the prevalence of hypertension increases sharply, emphasizing the importance of its prevention. This increased risk highlights the critical need for effective prevention strategies specifically designed for this population. To address this issue, the present study aimed to identify easily measurable risk factors that contribute to hypertension in postmenopausal women using explainable artificial intelligence (XAI) and machine learning (ML) techniques. This study conducted hypertension classification by analyzing health checkup data from 3289 postmenopausal Korean women aged 55-79 years, extracted from the 2022-2023 Korea National Health Insurance Service (KNHIS) database, using XGBoost, SVM and ANN. XGBoost was the most effective model (AUC: 92.12%, MCC: 0.71) in hypertension classification. Shapley Additive exPlanations-based feature importance identified age and waist circumference (WC) as the most important risk factors for hypertension. In this study, blood pressure increased with variations in WC, a modifiable risk factor. These findings suggest that WC should be managed more strictly to prevent hypertension in postmenopausal women.

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来源期刊
Bioengineering
Bioengineering Chemical Engineering-Bioengineering
CiteScore
4.00
自引率
8.70%
发文量
661
期刊介绍: Aims Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal: ● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings. ● Manuscripts regarding research proposals and research ideas will be particularly welcomed. ● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. ● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds. Scope ● Bionics and biological cybernetics: implantology; bio–abio interfaces ● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices ● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc. ● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology ● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering ● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation ● Translational bioengineering
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