用于生物医学和疾病治疗的食用家畜血液制品

IF 3.6 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Current Research in Biotechnology Pub Date : 2025-01-01 DOI:10.1016/j.crbiot.2025.100308

Zhi Cao , Imran Mahmood Khan , Xiangrui Niu , Yang Hu , Zhuang Duan , Qiang Fang , Zhouping Wang , Junsong Yang

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引用次数: 0

摘要

家畜食用血制品是屠宰过程中产生的高价值衍生物，在生物医学和疾病治疗方面具有巨大潜力。家畜血液中含有丰富的蛋白质、多肽、铁、维生素等生物活性物质。其中功能蛋白和肽因其在药物传递、免疫调节、抗感染和抗氧化等方面的突出作用而受到广泛研究。它们显著影响癌症治疗和免疫调节，为食品和制药行业的创新提供宝贵的资源。牲畜血液制品的开发和利用为疾病治疗提供了创新的解决方案，并通过减少血液废物的环境负担来促进食品和制药行业的可持续发展。然而，诸如血液成分的复杂性、生物活性化合物有效性的可变性以及对先进纯化技术的需求等挑战限制了它们的广泛应用。此外，必须解决治疗适宜性的监管和安全问题。本文综述了家畜血液制品在生物医学中的生物医学应用的最新进展，解决了这些挑战，并强调了它们在减少环境浪费和促进可持续发展方面的潜力。这篇综述巩固了现有的知识，为未来的研究提供了基础，促进了疾病干预和治疗的创新，同时解决了利用障碍。

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Edible domestic animal blood products for biomedical and disease treatment applications

Edible blood products from domestic livestock are high-value derivatives produced during slaughter, with significant potential in biomedicine and disease treatment. Livestock blood is rich in proteins, peptides, iron, vitamins and other bioactive substances. Among them, functional proteins and peptides have been widely studied for their prominent roles in drug delivery, immune regulation, anti-infection and antioxidation. They significantly impact cancer treatment and immune regulation, providing valuable resources for innovation in the food and pharmaceutical industries. The development and utilization of livestock blood products offer innovative solutions for disease treatment and promote the sustainable development of the food and pharmaceutical industries by reducing the environmental burden of blood waste. However, challenges such as the complexity of blood composition, the variability of bioactive compound effectiveness, and the need for advanced purification techniques limit their broader applications. Additionally, regulatory and safety concerns must be addressed for therapeutic suitability. This review highlights the recent advancements in the biomedical applications of livestock blood products in biomedicine, addressing these challenges and emphasizing their potential to reduce environmental waste and promote sustainable development. This review consolidates current knowledge to provide a foundation for future research, fostering innovation in disease intervention and therapy while addressing utilization barriers.

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来源期刊

Current Research in Biotechnology Biochemistry, Genetics and Molecular Biology-Biotechnology

CiteScore

6.70

自引率

3.60%

发文量

审稿时长

38 days

期刊介绍： Current Research in Biotechnology (CRBIOT) is a new primary research, gold open access journal from Elsevier. CRBIOT publishes original papers, reviews, and short communications (including viewpoints and perspectives) resulting from research in biotechnology and biotech-associated disciplines. Current Research in Biotechnology is a peer-reviewed gold open access (OA) journal and upon acceptance all articles are permanently and freely available. It is a companion to the highly regarded review journal Current Opinion in Biotechnology (2018 CiteScore 8.450) and is part of the Current Opinion and Research (CO+RE) suite of journals. All CO+RE journals leverage the Current Opinion legacy-of editorial excellence, high-impact, and global reach-to ensure they are a widely read resource that is integral to scientists' workflow.