{"title":"毒品犯孟乔森代理综合症:我们何时敢于关心,为什么敢于关心","authors":"Pascale Basilicata, Angela Simonelli, Mariagrazia Marisei, Angela Silvestre, Rossella Guadagni, Maria Pieri","doi":"10.1016/j.legalmed.2025.102659","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The term Munchausen syndrome by proxy (MSP) refers to a situation in which one or both parents by procuring or inventing symptoms or illness that their children do not have. As a consequence children can be exposed to continual medical examinations, tests and analyses, including surgery that can severely injure or, in extreme cases, provoke death. Usually, the victim is a young child, and the perpetrator is the mother, usually the person child is almost exclusively entrusted, placing her in the best position to simulate illness. Difficulty in making a diagnosis is motivated by the low prevalence of cases, unspecific nature of the symptoms, difficulty of reconducting the overcure back to a criminal case and tracing it back to the care giver.</div></div><div><h3>Objective</h3><div>Starting from a case series, a diagnostic algorithm useful for prompt MSP identification has been developed.</div></div><div><h3>Participants and setting</h3><div>A detailed examination of four cases is given, all with a common feature: drug administration to perpetrate MSP.</div></div><div><h3>Methods</h3><div>Biological fluids have been sampled and analyzed for drugs to which symptomatology could be traced.</div></div><div><h3>Results</h3><div>In all presented cases a late MSP diagnosis was possible on the base of results from toxicological analyses. Although analytical results are often diagnostic, a delay in sample collection, related to improper diagnostic algorithm, is frequent. Only an integrated approach, based on collaboration among multiple professionals, among which the role of the medico-legal expert and toxicologist stands out, can ensure the achievement of a rapid diagnosis and the protection of the victim.</div></div>","PeriodicalId":49913,"journal":{"name":"Legal Medicine","volume":"76 ","pages":"Article 102659"},"PeriodicalIF":1.3000,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Drug-perpetrated Munchausen by proxy syndrome: When we dare and why we dare to care\",\"authors\":\"Pascale Basilicata, Angela Simonelli, Mariagrazia Marisei, Angela Silvestre, Rossella Guadagni, Maria Pieri\",\"doi\":\"10.1016/j.legalmed.2025.102659\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>The term Munchausen syndrome by proxy (MSP) refers to a situation in which one or both parents by procuring or inventing symptoms or illness that their children do not have. As a consequence children can be exposed to continual medical examinations, tests and analyses, including surgery that can severely injure or, in extreme cases, provoke death. Usually, the victim is a young child, and the perpetrator is the mother, usually the person child is almost exclusively entrusted, placing her in the best position to simulate illness. Difficulty in making a diagnosis is motivated by the low prevalence of cases, unspecific nature of the symptoms, difficulty of reconducting the overcure back to a criminal case and tracing it back to the care giver.</div></div><div><h3>Objective</h3><div>Starting from a case series, a diagnostic algorithm useful for prompt MSP identification has been developed.</div></div><div><h3>Participants and setting</h3><div>A detailed examination of four cases is given, all with a common feature: drug administration to perpetrate MSP.</div></div><div><h3>Methods</h3><div>Biological fluids have been sampled and analyzed for drugs to which symptomatology could be traced.</div></div><div><h3>Results</h3><div>In all presented cases a late MSP diagnosis was possible on the base of results from toxicological analyses. Although analytical results are often diagnostic, a delay in sample collection, related to improper diagnostic algorithm, is frequent. Only an integrated approach, based on collaboration among multiple professionals, among which the role of the medico-legal expert and toxicologist stands out, can ensure the achievement of a rapid diagnosis and the protection of the victim.</div></div>\",\"PeriodicalId\":49913,\"journal\":{\"name\":\"Legal Medicine\",\"volume\":\"76 \",\"pages\":\"Article 102659\"},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2025-06-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Legal Medicine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1344622325000938\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, LEGAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Legal Medicine","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1344622325000938","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, LEGAL","Score":null,"Total":0}
Drug-perpetrated Munchausen by proxy syndrome: When we dare and why we dare to care
Background
The term Munchausen syndrome by proxy (MSP) refers to a situation in which one or both parents by procuring or inventing symptoms or illness that their children do not have. As a consequence children can be exposed to continual medical examinations, tests and analyses, including surgery that can severely injure or, in extreme cases, provoke death. Usually, the victim is a young child, and the perpetrator is the mother, usually the person child is almost exclusively entrusted, placing her in the best position to simulate illness. Difficulty in making a diagnosis is motivated by the low prevalence of cases, unspecific nature of the symptoms, difficulty of reconducting the overcure back to a criminal case and tracing it back to the care giver.
Objective
Starting from a case series, a diagnostic algorithm useful for prompt MSP identification has been developed.
Participants and setting
A detailed examination of four cases is given, all with a common feature: drug administration to perpetrate MSP.
Methods
Biological fluids have been sampled and analyzed for drugs to which symptomatology could be traced.
Results
In all presented cases a late MSP diagnosis was possible on the base of results from toxicological analyses. Although analytical results are often diagnostic, a delay in sample collection, related to improper diagnostic algorithm, is frequent. Only an integrated approach, based on collaboration among multiple professionals, among which the role of the medico-legal expert and toxicologist stands out, can ensure the achievement of a rapid diagnosis and the protection of the victim.
期刊介绍:
Legal Medicine provides an international forum for the publication of original articles, reviews and correspondence on subjects that cover practical and theoretical areas of interest relating to the wide range of legal medicine.
Subjects covered include forensic pathology, toxicology, odontology, anthropology, criminalistics, immunochemistry, hemogenetics and forensic aspects of biological science with emphasis on DNA analysis and molecular biology. Submissions dealing with medicolegal problems such as malpractice, insurance, child abuse or ethics in medical practice are also acceptable.