萎缩型前列腺癌：一个诊断缺陷

Diagnostic Histopathology Pub Date : 2025-05-05 DOI:10.1016/j.mpdhp.2025.04.009

Ka Wing Eric Wong, Tanjot Singh, Jo-An Roulson

{"title":"萎缩型前列腺癌：一个诊断缺陷","authors":"Ka Wing Eric Wong, Tanjot Singh, Jo-An Roulson","doi":"10.1016/j.mpdhp.2025.04.009","DOIUrl":null,"url":null,"abstract":"<div><div>The atrophic pattern of prostatic adenocarcinoma is an uncommon histological pattern of acinar prostatic adenocarcinoma. Due to its deceptively benign histological appearance, it can be misdiagnosed as a benign entity. We report a case of atrophic pattern prostatic adenocarcinoma in an elderly male patient, highlighting key histopathological findings and prognostic implications. This pattern closely resembles benign atrophy, and we discuss the differences in architectural and cytological features, as well as the role of immunohistochemistry as a diagnostic adjunct. It is vital to recognise benign-appearing variants of prostatic adenocarcinoma to prevent misdiagnosis and ensure appropriate clinical management.</div></div>","PeriodicalId":39961,"journal":{"name":"Diagnostic Histopathology","volume":"31 7","pages":"Pages 447-450"},"PeriodicalIF":0.0000,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Atrophic-pattern prostatic adenocarcinoma: a diagnostic pitfall\",\"authors\":\"Ka Wing Eric Wong, Tanjot Singh, Jo-An Roulson\",\"doi\":\"10.1016/j.mpdhp.2025.04.009\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The atrophic pattern of prostatic adenocarcinoma is an uncommon histological pattern of acinar prostatic adenocarcinoma. Due to its deceptively benign histological appearance, it can be misdiagnosed as a benign entity. We report a case of atrophic pattern prostatic adenocarcinoma in an elderly male patient, highlighting key histopathological findings and prognostic implications. This pattern closely resembles benign atrophy, and we discuss the differences in architectural and cytological features, as well as the role of immunohistochemistry as a diagnostic adjunct. It is vital to recognise benign-appearing variants of prostatic adenocarcinoma to prevent misdiagnosis and ensure appropriate clinical management.</div></div>\",\"PeriodicalId\":39961,\"journal\":{\"name\":\"Diagnostic Histopathology\",\"volume\":\"31 7\",\"pages\":\"Pages 447-450\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-05-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Diagnostic Histopathology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1756231725000763\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic Histopathology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1756231725000763","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

萎缩型前列腺腺癌是一种罕见的腺泡性前列腺腺癌的组织学类型。由于其看似良性的组织学外观，它可能被误诊为良性实体。我们报告一位老年男性患者的萎缩性前列腺腺癌病例，强调关键的组织病理学结果和预后意义。这种模式与良性萎缩非常相似，我们讨论了结构和细胞学特征的差异，以及免疫组织化学作为诊断辅助手段的作用。它是至关重要的认识良性变异的前列腺腺癌，以防止误诊和确保适当的临床处理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Atrophic-pattern prostatic adenocarcinoma: a diagnostic pitfall

The atrophic pattern of prostatic adenocarcinoma is an uncommon histological pattern of acinar prostatic adenocarcinoma. Due to its deceptively benign histological appearance, it can be misdiagnosed as a benign entity. We report a case of atrophic pattern prostatic adenocarcinoma in an elderly male patient, highlighting key histopathological findings and prognostic implications. This pattern closely resembles benign atrophy, and we discuss the differences in architectural and cytological features, as well as the role of immunohistochemistry as a diagnostic adjunct. It is vital to recognise benign-appearing variants of prostatic adenocarcinoma to prevent misdiagnosis and ensure appropriate clinical management.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Diagnostic Histopathology Medicine-Pathology and Forensic Medicine

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.