接受丁丙诺啡治疗阿片类药物使用障碍的女性和男性失眠症状的社会心理相关性

IF 1.6 Q3 CLINICAL NEUROLOGY
NeuroSci Pub Date : 2025-05-30 DOI:10.3390/neurosci6020048
Sajanee Chithranjan, Michelle Eglovitch, Madison M Marcus, Dace Svikis, Maha Alattar, Caitlin E Martin
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引用次数: 0

摘要

失眠在阿片类药物使用障碍(OUD)患者中很常见。生物心理社会因素对睡眠健康很重要,但这种交叉关系尚未在服用丁丙诺啡治疗OUD的人群中得到充分阐明。目的是报告失眠症患者和非失眠症患者报告的生物心理社会因素,特别是门诊OUD治疗中的女性和男性。母研究招募了2022年2月至2023年9月期间稳定服用丁丙诺啡的成年人。失眠症严重程度指数(ISI)得分≥11分表明有临床上明显的失眠症。通过失眠症的存在来检测差异,使用卡方检验和Fisher精确检验对男性和女性进行分层。在所有参与者(N = 130)中,大多数(N = 77;59.2%)符合临床显著性失眠的标准。与没有失眠的女性相比,失眠女性更有可能报告社会压力因素,包括物质使用歧视(p = 0.040)、食物不安全(p = 0.032)和交通困难(p = 0.043)。失眠的男性比没有失眠的男性更有可能报告在获得医疗保健方面的经济困难(p = 0.023)。这些发现提供了一个独特的视角来考虑对接受OUD药物治疗的女性和男性进行睡眠干预的发展和实施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Psychosocial Correlates of Insomnia Symptoms Among Women and Men Receiving Buprenorphine Treatment for Opioid Use Disorder.

Insomnia is common in individuals with opioid use disorder (OUD). Biopsychosocial factors are important in sleep health, yet this intersection has yet to be fully elucidated in people on buprenorphine for OUD. The objective is to report on patient-reported biopsychosocial factors among people with and without insomnia, specifically among women and men in outpatient OUD treatment. The parent study enrolled adults stabilized on buprenorphine from February 2022-September 2023. Scores of ≥11 on the Insomnia Severity Index (ISI) indicated clinically significant insomnia. Differences were detected by the presence of insomnia, stratified by men and women, using chi-squared and Fisher's exact tests. Of the overall participants (N = 130), most (n = 77; 59.2%) met the criteria for clinically significant insomnia. Women with insomnia were more likely to report social stressors including discrimination for substance use (p = 0.040), food insecurity (p = 0.032), and transportation difficulties accessing healthcare (p = 0.043) than women without insomnia. Men with insomnia were more likely to report financial difficulties accessing healthcare (p = 0.023) than men without insomnia. These findings provide a unique perspective to consider in the development and implementation of sleep interventions for women and men receiving medication treatment for OUD.

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