病例报告:鞘内C1-C2侧穿刺巴氯芬治疗:脊髓损伤后另一种有效和安全的方法。

IF 2.5 Q2 CLINICAL NEUROLOGY
Frontiers in pain research (Lausanne, Switzerland) Pub Date : 2025-06-10 eCollection Date: 2025-01-01 DOI:10.3389/fpain.2025.1571716
Rayan Fawaz, Hayat Belaid, Baptiste Eklu, Jean Baptiste Thiebaut, Manon Duraffourg
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引用次数: 0

摘要

痉挛是一种神经系统疾病,在中枢神经系统损伤(如脊髓损伤)后,会破坏对肌肉张力的调节。巴氯芬是治疗痉挛最有效的药物,可以通过连接鞘内导管的泵输送。导管通常通过腰椎穿刺插入,并推进到与令人不安的痉挛相对应的水平。但这可能是不可能的,特别是当涉及到宫颈水平。我们报告了一例外伤性颈脊髓损伤后严重痉挛的患者,在通过腰椎穿刺放置导管失败后,成功地进行了侧位C1-2穿刺,将逆行导管置入C4水平。在8个月的随访期间,患者痉挛症状明显减轻,未见恶化。在创新的三维重建图像引导下,通过侧位C1-2穿刺放置导管,可以作为一种有效和安全的替代方法在颈椎水平输送巴氯芬。讨论了颈椎病的相关性,并考虑了所涉及的问题。ITB在宫颈水平的作用机制尚不完全清楚,这对于达到最佳临床效果,避免不良反应和并发症至关重要。临床病例发表较少;因此提出这个案例很重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Case Report: Lateral C1-C2 puncture for intrathecal baclofen therapy: an alternative effective and safe approach after spinal cord injury.

Case Report: Lateral C1-C2 puncture for intrathecal baclofen therapy: an alternative effective and safe approach after spinal cord injury.

Case Report: Lateral C1-C2 puncture for intrathecal baclofen therapy: an alternative effective and safe approach after spinal cord injury.

Spasticity is a neurological disorder that disrupts the regulation of muscle tone following an injury to the central nervous system, such as spinal cord injury. Baclofen is the most effective medication for treating spasticity and can be delivered via a pump connected to an intrathecal catheter. The catheter is typically inserted via a lumbar punction and advanced up to the level corresponding to the disturbing spasticity. But this may not be possible, especially when cervical level is involved. We present the case of a patient with severe spasticity after a traumatic cervical spinal cord injury who successfully underwent a lateral C1-2 puncture for placement of a retrograde catheter to the C4 level, after an unsuccessful attempt at catheter placement via a lumbar puncture. The patient experienced a significant reduction in spasticity with no reported worsening during the 8 months follow-up period. The catheter placement via a lateral C1-2 puncture guided by innovative imagery with 3D reconstruction, may serve as an effective and safe alternative to deliver baclofen at the cervical level. Relevance of cervical ITB is discussed and issues involved are considered. The mechanism of action of ITB at cervical level, which is far from fully clarified, is crucial to reach the best clinical outcome and avoid si de effects and complications. Few clinical cases were published; hence the importance to present this case.

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CiteScore
2.10
自引率
0.00%
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审稿时长
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